Gritstone Oncology Inc. (GRTS) stock declined by 10.19% in the last trading closed while the GRTS stock rises by 11.35% during the after-hours trading session as Gritstone Oncology reported that the first individual has been medicated with its candidate COVID-19 vaccine in a Phase 1 trial as part of GRTS’s “CORAL” program. Gritstone Oncology, a clinical-stage biotechnology firm focuses on the development of immunotherapies to treat a variety of cancers and infectious diseases.
What is happening?
In a Phase 1 trial, the first person has been dosed under Gritstone’s “CORAL” program with its COVID-19 vaccine. The researchers are investigating the immunogenicity and protection of delivering SARS-CoV-2 viral antigens using their self-amplifying mRNA (SAM) and/or adenoviral vectors, which contain both Spike and other viral antigens not included in currently approved vaccines. The National Institute of Allergy and Infectious Diseases (NIAID) is funding the Phase 1 study, which is being carried out by their Infectious Diseases Clinical Research Consortium.
In Phase 1 clinical trial which is a multicenter, open-label, dose- and age-escalation study in healthy adult participants to determine the immunogenicity and efficacy of Gritstone’s CORAL COVID-19 vaccine. In a parallel design, heterologous and homologous key vaccinations of the adenoviral vector and/or SAM vector representing SARS-CoV-2 Spike alone or Spike plus additional SARS-CoV-2 T cell epitopes are examined.
Gritstone through its CORAL program is expecting some visible results since it is considered as an efficient vaccine to counter the challenges faced by a coronavirus and also those which will possibly come out around novel Spike variants. Needless to say that COVID-19 is the most problematic thing that the world is going through for the past year and under such circumstances, GRTS bringing the efficient vaccine is definitely a remarkable achievement. Possibly due to this new positive development in Gritstone, the investors are making valuable investments in GRTS shares, Hence the GRTS stock price is rising in after-hours.