Apellis Pharmaceuticals (APLS) insider trading activity: Get Latest News Today

APLS Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares17.94

Short Percent Of Float24.48

Shares Outstanding125.52M

Shares Float84.23M

Shares Short22.51M

Short Ratio11.85

24.48%

Short % of Float

17.94%

Short % of Shares Outstanding

Market Insider APLS

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

13.86% Percentage of Shares held by All Insiders

103.48% Percentage of Shares held by All Institutions

120.12% Percentage of Float held by Institutions

375

Number of Institutions Holding Shares

Institutional Ownership

About 103.48% of APLS shares are held by financial institutions. DEUTSCHE BANK AG\ is the top corporate investor, holding 1.61M shares valued at $94.74M. A 1.36% stake in Apellis Pharmaceuticals, Inc. is owned by the company. GEODE CAPITAL MANAGEMENT, LLC owns 1.69M shares valued at $99.35M, which translates its holding of 1.42% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2024	DEUTSCHE BANK AG\	1.36%	1.61M	94.74M	754.77K	+88.07%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.42%	1.69M	99.35M	59.25K	+3.63%
Mar 31, 2024	BOXER CAPITAL, LLC	1.45%	1.73M	101.45M	0	0
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	1.71%	2.02M	118.95M	-121.39K	-5.66%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.34%	406.48K	23.89M	312.52K	+332.58%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.75%	885.17K	52.03M	0	0
Mar 31, 2024	MORGAN STANLEY	1.38%	1.64M	96.26M	-1.46M	-47.12%
Mar 31, 2024	JENNISON ASSOCIATES LLC	2.73%	3.24M	190.48M	-35.41K	-1.08%
Mar 31, 2024	BLACKROCK INC.	4.63%	5.49M	322.97M	113.34K	+2.11%
Mar 31, 2024	VANGUARD GROUP INC	8.01%	9.51M	558.75M	-49.81K	-0.52%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.88%	4.61M	270.73M	-1.7M	-26.93%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.41%	491.9K	28.91M	-124.38K	-20.18%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.42%	494.69K	29.08M	238.16K	+92.84%
Mar 31, 2024	FMR LLC	1.84%	2.18M	128.07M	86.28K	+4.12%
Mar 31, 2024	JPMORGAN CHASE & CO	1.87%	2.21M	130.16M	-359.82K	-13.98%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.07%	2.46M	144.56M	-1.09K	-0.04%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	2.37%	2.81M	164.99M	0	0
Mar 31, 2024	STATE STREET CORP	2.45%	2.91M	171.02M	-5.89K	-0.20%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.23%	270.58K	15.9M	56	+0.02%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.24%	287.28K	16.89M	135.08K	+88.75%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.22%	260.27K	15.3M	14.71K	+5.99%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.21%	245.56K	14.43M	-81K	-24.80%
Mar 31, 2024	FIDUCIARY TRUST CO	0.2%	240.99K	14.17M	-1.62K	-0.67%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.2%	232.24K	13.65M	232.24K	+100.00%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.19%	226.65K	13.32M	-3.14K	-1.37%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.19%	225K	13.23M	225K	+100.00%
Mar 31, 2024	MACQUARIE GROUP LTD	0.19%	221.65K	13.03M	-361.78K	-62.01%
Mar 31, 2024	ABRDN PLC	0.16%	189.81K	11.16M	20.76K	+12.28%
Mar 31, 2024	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.15%	178.4K	10.49M	78K	+77.68%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.14%	165K	9.7M	90K	+120.00%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	148.8K	8.75M	5.68K	+3.97%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.12%	145.83K	8.57M	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.12%	145.04K	8.53M	12.47K	+9.41%
Mar 31, 2024	SWISS NATIONAL BANK	0.12%	140.3K	8.25M	-22.1K	-13.61%
Mar 31, 2024	SENATOR INVESTMENT GROUP LP	0.12%	140K	8.23M	140K	+100.00%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.11%	132.94K	7.83M	-336.95K	-71.71%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	123.33K	7.25M	17.33K	+16.35%
Mar 31, 2024	RHUMBLINE ADVISERS	0.1%	120.92K	7.11M	-12.67K	-9.48%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.1%	115.45K	6.79M	56.18K	+94.78%
Mar 31, 2024	UBS GROUP AG	0.09%	111.29K	6.54M	16.26K	+17.11%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.08%	94.61K	5.56M	8.18K	+9.46%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.08%	92.66K	5.45M	92.66K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.08%	89.7K	5.27M	89.7K	+100.00%
Mar 31, 2024	LISANTI CAPITAL GROWTH, LLC	0.08%	89.21K	5.24M	42.91K	+92.66%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	12.69%	15.06M	885.11M	-1.39M	-8.44%
Mar 31, 2024	ECOR1 CAPITAL, LLC	9.57%	11.36M	667.59M	184.36K	+1.65%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	9.36%	11.11M	653.11M	0	0
Mar 31, 2024	CITADEL ADVISORS LLC	0.25%	293K	17.22M	-115.4K	-28.26%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.27%	319.48K	18.78M	8.89K	+2.86%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.27%	322.92K	18.98M	-49.33K	-13.25%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.27%	325.93K	19.16M	-14.58K	-4.28%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.27%	321.8K	18.92M	-623.9K	-65.97%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	0.34%	400K	23.51M	-225K	-36.00%
Mar 31, 2024	NORTHERN TRUST CORP	0.37%	440.46K	25.89M	-8.27K	-1.84%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.39%	459.4K	27M	-23.92K	-4.95%
Mar 31, 2024	BELLEVUE GROUP AG	0.4%	473.92K	27.86M	-347.89K	-42.33%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.42%	503.04K	29.57M	21.54K	+4.47%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	0.45%	531.36K	31.23M	-34.22K	-6.05%
Mar 31, 2024	IRON TRIANGLE PARTNERS LP	0.46%	550K	32.33M	550K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	584.93K	34.38M	247.42K	+73.31%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.61%	723.44K	42.52M	289.11K	+66.56%
Mar 31, 2024	INVESCO LTD.	0.64%	762.12K	44.8M	243.28K	+46.89%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.66%	785.4K	46.17M	772.87K	+6,169.63%
Mar 31, 2024	LOGOS GLOBAL MANAGEMENT LP	0.67%	800K	47.02M	-150K	-15.79%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.71%	845.53K	50.49M	399.53K	+89.58%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.78%	924.56K	54.35M	20.15K	+2.23%
Mar 31, 2024	FIERA CAPITAL CORP	0.8%	948.44K	55.75M	29.35K	+3.19%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.84%	1M	58.78M	1M	+100.00%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	0.89%	1.05M	61.98M	1K	+0.09%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.9%	1.07M	63.03M	-271.33K	-20.18%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.09%	1.3M	76.28M	375.6K	+40.73%
Mar 31, 2024	ARTAL GROUP S.A.	1.11%	1.32M	77.31M	-106.06K	-7.46%
Dec 31, 2023	EAGLE ASSET MANAGEMENT INC	0.37%	446K	26.7M	-3.97K	-0.88%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	13.67%	16.45M	984.42M	16.45M	+100.00%
Dec 31, 2023	ECOR1 CAPITAL, LLC	9.29%	11.17M	668.82M	273.21K	+2.51%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	9.24%	11.11M	665.11M	0	0
Dec 31, 2023	VANGUARD GROUP INC	7.94%	9.56M	572M	85.7K	+0.91%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	5.24%	6.3M	377.33M	-215.89K	-3.31%
Dec 31, 2023	BLACKROCK INC.	4.47%	5.38M	322.12M	108.51K	+2.06%
Dec 31, 2023	JENNISON ASSOCIATES LLC	2.72%	3.28M	196.1M	-266.29K	-7.52%
Dec 31, 2023	MORGAN STANLEY	2.57%	3.1M	185.39M	1.49M	+92.49%
Dec 31, 2023	STATE STREET CORP	2.42%	2.92M	174.52M	-322.69K	-9.97%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	2.33%	2.81M	168.03M	-323.02K	-10.32%
Dec 31, 2023	JPMORGAN CHASE & CO	2.14%	2.57M	154.09M	356.39K	+16.07%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.05%	2.46M	147.28M	677.1K	+37.97%
Dec 31, 2023	ASSENAGON ASSET MANAGEMENT S.A.	1.78%	2.15M	128.4M	1.12M	+109.57%
Dec 31, 2023	FMR LLC	1.74%	2.09M	125.25M	-167.3K	-7.40%
Dec 31, 2023	BOXER CAPITAL, LLC	1.43%	1.73M	103.32M	0	0
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.36%	1.63M	97.63M	75.82K	+4.88%
Dec 31, 2023	ARTAL GROUP S.A.	1.18%	1.42M	85.08M	-243.23K	-14.61%
Dec 31, 2023		1.12%	1.34M	80.49M	610.41K	+83.15%
Dec 31, 2023	NORGES BANK	0.79%	946.21K	56.64M	946.21K	+100.00%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	0.88%	1.05M	63.06M	-435	-0.04%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	0.79%	950K	56.87M	200K	+26.67%
Dec 31, 2023	ORBIMED ADVISORS LLC	0.77%	922.2K	55.2M	-338.3K	-26.84%
Dec 31, 2023	FIERA CAPITAL CORP	0.76%	919.09K	55.02M	-600	-0.07%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.75%	904.41K	54.14M	25.05K	+2.85%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.74%	885.17K	52.99M	271.12K	+44.15%
Dec 31, 2023	DEUTSCHE BANK AG\	0.71%	857K	51.3M	532.71K	+164.27%
Dec 31, 2023	BELLEVUE GROUP AG	0.68%	821.8K	49.19M	27.96K	+3.52%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	0.52%	625K	37.41M	-1.38M	-68.75%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.51%	616.27K	36.89M	-122.24K	-16.55%
Dec 31, 2023	MACQUARIE GROUP LTD	0.49%	583.43K	34.92M	-493.12K	-45.81%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	0.47%	565.58K	33.86M	213.19K	+60.50%
Dec 31, 2023	INVESCO LTD.	0.43%	518.84K	31.06M	-21.84K	-4.04%
Dec 31, 2023	PORTMAN SQUARE CAPITAL LLP	0.42%	500K	29.93M	292.5K	+140.96%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.4%	483.32K	28.93M	112.47K	+30.33%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.4%	481.5K	28.82M	300.18K	+165.55%
Dec 31, 2023	BANK OF MONTREAL /CAN/	0.39%	469.88K	29.61M	37.91K	+8.78%
Dec 31, 2023	NORTHERN TRUST CORP	0.37%	448.73K	26.86M	-1.7K	-0.38%
Dec 31, 2023	JANE STREET GROUP, LLC	0.36%	434.7K	26.02M	161.48K	+59.10%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.36%	434.34K	26M	-270.62K	-38.39%
Dec 31, 2023	CITADEL ADVISORS LLC	0.33%	394.9K	23.64M	-285K	-41.92%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.28%	336.4K	20.14M	-250.8K	-42.71%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.31%	372.26K	22.28M	11.97K	+3.32%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.28%	340.51K	20.38M	-62.44K	-15.50%
Dec 31, 2023	CANDRIAM S.C.A.	0.28%	337.51K	20.2M	11K	+3.37%
Dec 31, 2023	PRUDENTIAL FINANCIAL INC	0.27%	326.56K	19.55M	23K	+7.58%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.26%	310.58K	18.59M	-21.21K	-6.39%
Sep 30, 2023	AVORO CAPITAL ADVISORS LLC	9.31%	11.11M	-	0	0
Sep 30, 2023	PORTMAN SQUARE CAPITAL LLP	0.17%	207.5K	-	207.5K	+100.00%
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.18%	214.16K	-	121.89K	+132.11%
Sep 30, 2023	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.18%	215K	-	25K	+13.16%
Sep 30, 2023	GROUP ONE TRADING, L.P.	0.19%	226.68K	-	207.87K	+1,104.61%
Sep 30, 2023	BNP PARIBAS ARBITRAGE, SNC	0.2%	236.36K	-	177.69K	+302.92%
Sep 30, 2023	FIDUCIARY TRUST CO	0.22%	265.21K	-	-8.71K	-3.18%
Sep 30, 2023	JANE STREET GROUP, LLC	0.23%	273.23K	-	-207.86K	-43.21%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.23%	273.51K	-	11.12K	+4.24%
Sep 30, 2023	AMUNDI	0.23%	278.96K	-	242.86K	+672.67%
Sep 30, 2023	BANK OF NOVA SCOTIA	0.25%	293.31K	-	288.69K	+6,248.59%
Sep 30, 2023	PRUDENTIAL FINANCIAL INC	0.25%	303.56K	-	126.48K	+71.43%
Sep 30, 2023	DEUTSCHE BANK AG\	0.27%	324.29K	-	-154.07K	-32.21%
Sep 30, 2023	CANDRIAM S.C.A.	0.27%	326.51K	-	0	0
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.28%	331.79K	-	-303.1K	-47.74%
Sep 30, 2023	BARCLAYS PLC	0.29%	342.89K	-	30.66K	+9.82%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.3%	352.39K	-	211.31K	+149.79%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.3%	360.29K	-	3K	+0.84%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.31%	370.86K	-	-107.87K	-22.53%
Sep 30, 2023	FIRST TRUST ADVISORS LP	0.33%	398.14K	-	320.85K	+415.12%
Sep 30, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.34%	402.94K	-	101.95K	+33.87%
Sep 30, 2023	BANK OF MONTREAL /CAN/	0.36%	431.97K	-	354.05K	+454.34%
Sep 30, 2023	EAGLE ASSET MANAGEMENT INC	0.38%	449.97K	-	-962	-0.21%
Sep 30, 2023	NORTHERN TRUST CORP	0.38%	450.43K	-	-401.84K	-47.15%
Sep 30, 2023	INVESCO LTD.	0.45%	540.68K	-	-611.72K	-53.08%
Sep 30, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	0.46%	548.87K	-	-47.36K	-7.94%
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.49%	587.2K	-	421.7K	+254.80%
Sep 30, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.51%	614.04K	-	614.04K	+100.00%
Sep 30, 2023		0.62%	734.15K	-	734.15K	+100.00%
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.62%	738.51K	-	337.55K	+84.19%
Sep 30, 2023	BELLEVUE GROUP AG	0.67%	793.84K	-	275.35K	+53.10%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.74%	879.36K	-	50.84K	+6.14%
Sep 30, 2023	FIERA CAPITAL CORP	0.77%	919.69K	-	391.77K	+74.21%
Sep 30, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.86%	1.02M	-	524.8K	+105.23%
Sep 30, 2023	POLAR CAPITAL HOLDINGS PLC	0.88%	1.05M	-	588.88K	+126.64%
Sep 30, 2023	ORBIMED ADVISORS LLC	1.06%	1.26M	-	350.3K	+38.49%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.3%	1.55M	-	56.44K	+3.77%
Sep 30, 2023	MORGAN STANLEY	1.35%	1.61M	-	852.33K	+112.64%
Sep 30, 2023	ARTAL GROUP S.A.	1.4%	1.66M	-	614.51K	+58.52%
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	1.68%	2M	-	690K	+52.67%
Sep 30, 2023	SLATE PATH CAPITAL LP	1.73%	2.07M	-	2.07M	+100.00%
Sep 30, 2023	FMR LLC	1.89%	2.26M	-	-1.97M	-46.52%
Sep 30, 2023	JENNISON ASSOCIATES LLC	2.97%	3.54M	-	1.57M	+79.75%
Sep 30, 2023	BLACKROCK INC.	4.42%	5.27M	-	-474.88K	-8.26%
Sep 30, 2023	ECOR1 CAPITAL, LLC	9.14%	10.9M	-	5.45M	+99.94%

APLS Insiders

Among the APLS insiders holding of 13.86% of the stake in company, DESCHATELETS PASCAL, Chief Scientific Officer, holds the largest shares of 1.15M. FRANCOIS CEDRIC, Chief Executive Officer, is the second largest APLS insider with ownership of 415.7K shares. MACHIELS ALEC, director, stands third with possession of 367.42K shares of that stake.

Insiders	Designation	Shares Held
DESCHATELETS PASCAL	Chief Scientific Officer	1.15M
FRANCOIS CEDRIC	Chief Executive Officer	415.7K
MACHIELS ALEC	director	367.42K
WATSON DAVID O.	General Counsel	138.73K
SULLIVAN TIMOTHY EUGENE	Chief Financial Officer	128.67K
DUNLOP A. SINCLAIR	director	100K
GROSSI FEDERICO	Chief Medical Officer	94.88K
TOWNSEND ADAM J.	Chief Commercial Officer	84.05K
DELONG MARK JEFFREY	Chief Business & Strat Officer	83.95K
NICHOLSON NUR	Chief Technical Officer	83.66K
LEWIS KAREN	Chief People Officer	70.25K
SCHEIBLER LUKAS	Chief Research Officer	68.3K
EISELE JEFFREY	Chief Development Officer	55.31K
BAUMAL CAROLINE	Chief Medical Officer	53.71K
CHOPAS JAMES GEORGE	VP/Chief Accounting Officer	47.96K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 17, 2025	CHOPAS JAMES GEORGE	SALE	24.82	183	4.54K	47.96K
Mar 05, 2025	WATSON DAVID O.	SALE	25.10	5.57K	139.79K	138.73K
Feb 11, 2025	DELONG MARK JEFFREY	SALE	28.54	363	10.36K	83.95K
Jan 29, 2025	TOWNSEND ADAM J.	SALE	29.52	695	20.52K	84.05K
Jan 29, 2025	DELONG MARK JEFFREY	SALE	29.52	365	10.78K	84.31K
Jan 29, 2025	FRANCOIS CEDRIC	SALE	29.52	2.82K	83.37K	415.7K
Jan 29, 2025	DESCHATELETS PASCAL	SALE	29.52	826	24.39K	1.15M
Jan 29, 2025	EISELE JEFFREY	SALE	29.52	278	8.21K	55.31K
Jan 29, 2025	NICHOLSON NUR	SALE	29.52	825	24.36K	83.66K
Jan 29, 2025	LEWIS KAREN	SALE	29.52	364	10.75K	70.25K
Jan 29, 2025	SULLIVAN TIMOTHY EUGENE	SALE	29.52	546	16.12K	128.67K
Jan 29, 2025	WATSON DAVID O.	SALE	29.52	695	20.52K	144.3K
Jan 22, 2025	LEWIS KAREN	SALE	30.43	1.75K	53.28K	70.62K
Jan 22, 2025	SULLIVAN TIMOTHY EUGENE	SALE	30.43	3.09K	93.95K	129.21K
Jan 22, 2025	DESCHATELETS PASCAL	SALE	30.43	3.95K	120.12K	1.15M
Jan 22, 2025	EISELE JEFFREY	SALE	30.43	1.29K	39.28K	55.59K
Jan 22, 2025	TOWNSEND ADAM J.	SALE	30.43	3.32K	101.1K	84.75K
Jan 22, 2025	WATSON DAVID O.	SALE	30.43	3.32K	101.1K	144.99K
Jan 22, 2025	CHOPAS JAMES GEORGE	SALE	30.43	1.1K	33.35K	48.14K
Jan 22, 2025	DELONG MARK JEFFREY	SALE	30.43	1.4K	42.47K	84.67K
Jan 22, 2025	FRANCOIS CEDRIC	SALE	30.43	13.55K	412.3K	418.52K
Jan 22, 2025	NICHOLSON NUR	SALE	30.43	3.95K	120.12K	84.49K
Jan 17, 2025	LEWIS KAREN	SALE	29.96	1.24K	37.18K	43.86K
Jan 17, 2025	NICHOLSON NUR	SALE	29.96	2.15K	64.26K	52.01K
Jan 17, 2025	BAUMAL CAROLINE	SALE	29.96	1.85K	55.51K	53.71K
Jan 17, 2025	CHOPAS JAMES GEORGE	SALE	29.96	715	21.42K	36.64K
Jan 17, 2025	SULLIVAN TIMOTHY EUGENE	SALE	29.96	1.73K	51.83K	86.37K
Jan 17, 2025	TOWNSEND ADAM J.	SALE	29.96	2.2K	65.94K	88.07K
Jan 17, 2025	WATSON DAVID O.	SALE	29.96	2.2K	65.94K	105.56K
Jan 17, 2025	DELONG MARK JEFFREY	SALE	29.96	1.24K	37K	57.56K
Jan 17, 2025	DESCHATELETS PASCAL	SALE	29.96	750	22.47K	1.14M
Jan 17, 2025	FRANCOIS CEDRIC	SALE	29.96	6.01K	179.96K	301.41K
Jan 13, 2025	DESCHATELETS PASCAL	SALE	28.70	2.29K	65.67K	1.14M
Jan 13, 2025	CHOPAS JAMES GEORGE	SALE	28.70	783	22.47K	37.36K
Jan 13, 2025	DELONG MARK JEFFREY	SALE	28.70	1.6K	45.89K	58.8K
Jan 13, 2025	EISELE JEFFREY	SALE	28.70	264	7.58K	56.88K
Jan 13, 2025	SULLIVAN TIMOTHY EUGENE	SALE	28.70	2.17K	62.28K	88.1K
Jan 13, 2025	TOWNSEND ADAM J.	SALE	28.70	2.69K	77.07K	90.27K
Jan 13, 2025	WATSON DAVID O.	SALE	28.70	4.97K	142.51K	107.76K
Jan 13, 2025	FRANCOIS CEDRIC	SALE	28.70	6.25K	179.3K	307.42K
Jan 13, 2025	LEWIS KAREN	SALE	28.70	1.6K	45.89K	45.1K
Jan 13, 2025	NICHOLSON NUR	SALE	28.70	2.63K	75.54K	54.16K
Jan 06, 2025	BAUMAL CAROLINE	SALE	33.81	2.82K	95.21K	55.56K
Dec 23, 2024	EISELE JEFFREY	SALE	33.09	63	2.08K	57.15K
Sep 16, 2024	CHOPAS JAMES GEORGE	SALE	36.21	192	6.95K	38.14K
Sep 16, 2024	DUNLOP A. SINCLAIR	SALE	36.79	7.52K	276.81K	100K
Sep 03, 2024	CHOPAS JAMES GEORGE	SALE	39.49	550	21.72K	38.33K
Jun 21, 2024	DUNLOP A. SINCLAIR	SALE	39.63	1.7K	67.17K	137K
May 08, 2024	DESCHATELETS PASCAL	SALE	44.02	100	4.4K	1.12M
Apr 08, 2024	DESCHATELETS PASCAL	SALE	54.92	4.73K	259.64K	1.12M
Apr 01, 2024	SULLIVAN TIMOTHY EUGENE	SALE	58.66	4K	234.64K	93.34K
Mar 19, 2024	DUNLOP A. SINCLAIR	SALE	57.18	18.68K	1.07M	174K
Mar 18, 2024	DELONG MARK JEFFREY	SALE	56.90	9.91K	564.05K	54.69K
Mar 15, 2024	CHOPAS JAMES GEORGE	SALE	56.46	184	10.39K	38.88K
Mar 13, 2024	NICHOLSON NUR	SALE	58.13	3.45K	200.68K	56.29K
Mar 08, 2024	DESCHATELETS PASCAL	SALE	63.35	100	6.34K	1.12M
Mar 01, 2024	SULLIVAN TIMOTHY EUGENE	SALE	63.95	2K	127.9K	93.34K
Mar 01, 2024	FRANCOIS CEDRIC	SALE	65.68	413	27.13K	313.66K
Feb 12, 2024	SULLIVAN TIMOTHY EUGENE	SALE	67.77	1.43K	96.97K	93.34K
Feb 12, 2024	DELONG MARK JEFFREY	SALE	67.77	597	40.46K	64.61K
Feb 12, 2024	DESCHATELETS PASCAL	SALE	67.77	1.15K	77.8K	1.12M
Feb 12, 2024	WATSON DAVID O.	SALE	67.77	781	52.93K	103.39K
Feb 12, 2024	FRANCOIS CEDRIC	SALE	67.77	3.96K	268.49K	313.66K
Feb 12, 2024	TOWNSEND ADAM J.	SALE	67.77	1.15K	77.8K	92.45K
Jan 30, 2024	EISELE JEFFREY	SALE	65.53	971	63.63K	57.21K
Jan 30, 2024	LEWIS KAREN	SALE	65.53	883	57.86K	46.39K
Jan 29, 2024	NICHOLSON NUR	SALE	64.14	835	53.56K	67.51K
Jan 29, 2024	DESCHATELETS PASCAL	SALE	64.14	874	56.06K	1.12M
Jan 29, 2024	DELONG MARK JEFFREY	SALE	64.14	367	23.54K	65.2K
Jan 29, 2024	LEWIS KAREN	SALE	64.14	367	23.54K	47.27K
Jan 29, 2024	TOWNSEND ADAM J.	SALE	64.14	906	58.11K	93.6K
Jan 29, 2024	SULLIVAN TIMOTHY EUGENE	SALE	64.14	906	58.11K	94.77K
Jan 29, 2024	WATSON DAVID O.	SALE	64.14	906	58.11K	104.17K
Jan 29, 2024	EISELE JEFFREY	SALE	64.14	279	17.89K	58.18K
Jan 29, 2024	FRANCOIS CEDRIC	SALE	64.14	2.84K	182.34K	317.62K
Jan 23, 2024	EISELE JEFFREY	SALE	63.69	7.38K	469.9K	58.46K
Jan 23, 2024	LEWIS KAREN	SALE	63.69	4.29K	272.98K	47.64K
Jan 22, 2024	FRANCOIS CEDRIC	SALE	65.00	13.43K	872.96K	320.47K
Jan 22, 2024	DELONG MARK JEFFREY	SALE	65.00	1.38K	89.95K	65.57K
Jan 22, 2024	WATSON DAVID O.	SALE	65.00	4.18K	271.94K	105.08K
Jan 22, 2024	TOWNSEND ADAM J.	SALE	65.00	3.41K	221.83K	94.51K
Jan 22, 2024	SULLIVAN TIMOTHY EUGENE	SALE	65.00	3.55K	230.8K	95.68K
Jan 22, 2024	EISELE JEFFREY	SALE	65.00	1.61K	104.45K	65.84K
Jan 22, 2024	CHOPAS JAMES GEORGE	SALE	65.00	1.06K	68.96K	39.07K
Jan 22, 2024	NICHOLSON NUR	SALE	65.00	2.59K	168.53K	68.34K
Jan 22, 2024	LEWIS KAREN	SALE	65.00	1.74K	112.96K	51.92K
Jan 22, 2024	DESCHATELETS PASCAL	SALE	65.00	3.91K	254.33K	1.12M
Jan 17, 2024	EISELE JEFFREY	SALE	65.58	5.21K	341.48K	67.44K
Jan 17, 2024	LEWIS KAREN	SALE	65.58	3.28K	214.84K	53.66K
Jan 16, 2024	EISELE JEFFREY	SALE	66.81	438	29.26K	72.65K
Jan 16, 2024	DELONG MARK JEFFREY	SALE	66.81	1.63K	108.96K	66.95K
Jan 16, 2024	SULLIVAN TIMOTHY EUGENE	SALE	66.81	2.24K	149.32K	99.23K
Jan 16, 2024	WATSON DAVID O.	SALE	66.81	4.24K	283.27K	109.26K
Jan 16, 2024	DESCHATELETS PASCAL	SALE	66.81	1.63K	109.03K	1.12M
Jan 16, 2024	LEWIS KAREN	SALE	66.81	1.63K	109.03K	56.94K
Jan 16, 2024	NICHOLSON NUR	SALE	66.81	1.86K	124.06K	70.94K
Jan 16, 2024	TOWNSEND ADAM J.	SALE	66.81	2.24K	149.32K	97.92K
Jan 16, 2024	CHOPAS JAMES GEORGE	SALE	66.81	864	57.72K	40.13K
Jan 16, 2024	FRANCOIS CEDRIC	SALE	66.81	7.85K	524.51K	333.9K
Jan 04, 2024	BAUMAL CAROLINE	SALE	60.05	2.75K	165.21K	32.93K
Dec 27, 2023	EISELE JEFFREY	SALE	60.23	235	14.15K	53.58K
Dec 26, 2023	EISELE JEFFREY	SALE	57.86	68	3.93K	53.82K
Dec 19, 2023	WATSON DAVID O.	SALE	57.38	2.3K	131.98K	89.75K
Dec 01, 2023	DUNLOP A. SINCLAIR	SALE	61.13	24K	1.47M	192.68K
Dec 01, 2023	SCHEIBLER LUKAS	SALE	60.00	10K	600K	68.3K
Dec 01, 2023	TOWNSEND ADAM J.	SALE	61.31	42.44K	2.6M	76.41K
Nov 30, 2023	SULLIVAN TIMOTHY EUGENE	SALE	54.79	300	16.44K	77.71K
Nov 21, 2023	FRANCOIS CEDRIC	SALE	48.80	5K	244K	269.66K
Nov 17, 2023	DUNLOP A. SINCLAIR	SALE	49.99	8.89K	444.62K	122.4K
Nov 17, 2023	MACHIELS ALEC	SALE	47.74	1.25K	59.68K	367.42K
Nov 08, 2023	DESCHATELETS PASCAL	SALE	47.27	12K	567.24K	1.07M
Oct 23, 2023	DELONG MARK JEFFREY	SALE	46.04	131	6.03K	51.62K
Oct 23, 2023	CHOPAS JAMES GEORGE	SALE	46.04	132	6.08K	32.68K
Oct 17, 2023	MACHIELS ALEC	SALE	48.50	1.25K	60.63K	367.42K
Oct 17, 2023	DUNLOP A. SINCLAIR	SALE	49.00	24K	1.18M	216.68K
Oct 09, 2023	DESCHATELETS PASCAL	SALE	40.38	12K	484.56K	1.07M
Sep 18, 2023	MACHIELS ALEC	SALE	45.00	1.25K	56.25K	367.42K
Sep 18, 2023	NICHOLSON NUR	SALE	46.15	10.63K	490.59K	53.28K
Sep 15, 2023	MACHIELS ALEC	SALE	45.34	1.25K	56.68K	367.42K
Sep 08, 2023	DESCHATELETS PASCAL	SALE	42.87	12K	514.44K	1.06M
Sep 06, 2023	SCHEIBLER LUKAS	SALE	43.01	1.76K	75.53K	68.3K
Sep 01, 2023	FRANCOIS CEDRIC	SALE	42.44	10.28K	436.45K	424.66K
Aug 31, 2023	CHOPAS JAMES GEORGE	SALE	41.23	551	22.72K	30.31K
Aug 08, 2023	DESCHATELETS PASCAL	SALE	23.66	12K	283.92K	1.05M
Jul 17, 2023	MACHIELS ALEC	SALE	64.79	1.25K	80.99K	267.64K
Jul 10, 2023	DESCHATELETS PASCAL	SALE	84.55	12K	1.01M	1.05M
Jul 03, 2023	SULLIVAN TIMOTHY EUGENE	SALE	91.10	300	27.33K	77.71K
Jul 03, 2023	WATSON DAVID O.	SALE	89.98	8.51K	765.73K	85.75K
Jun 20, 2023	MACHIELS ALEC	SALE	88.41	1.25K	110.51K	267.64K
Jun 08, 2023	DESCHATELETS PASCAL	SALE	91.35	12K	1.1M	1.04M
Jun 05, 2023	SULLIVAN TIMOTHY EUGENE	SALE	90.60	1.6K	144.97K	145.89K
Jun 01, 2023	LEWIS KAREN	SALE	86.00	5K	430K	41.5K
May 17, 2023	MACHIELS ALEC	SALE	88.66	1.25K	110.83K	267.64K
May 16, 2023	FRANCOIS CEDRIC	SALE	83.17	934	77.68K	303.72K
May 08, 2023	DESCHATELETS PASCAL	SALE	92.39	12K	1.11M	1.03M
May 03, 2023	TOWNSEND ADAM J.	SALE	82.71	5K	413.55K	76K
Apr 18, 2023	FRANCOIS CEDRIC	SALE	82.02	30K	2.46M	637.6K
Apr 17, 2023	MACHIELS ALEC	SALE	81.05	1.25K	101.31K	267.64K
Apr 10, 2023	DESCHATELETS PASCAL	SALE	78.21	12K	938.52K	1.03M
Apr 03, 2023	TOWNSEND ADAM J.	SALE	74.05	5K	370.25K	76K
Apr 03, 2023	LEWIS KAREN	SALE	75.00	5K	375K	41.43K
Apr 03, 2023	DUNLOP A. SINCLAIR	SALE	74.05	500	37.03K	131.3K
Mar 21, 2023	FRANCOIS CEDRIC	SALE	62.74	30K	1.88M	1.14M
Mar 17, 2023	MACHIELS ALEC	SALE	64.03	1.25K	80.04K	267.64K
Mar 08, 2023	DESCHATELETS PASCAL	SALE	63.79	12K	765.48K	1.02M
Mar 03, 2023	TOWNSEND ADAM J.	SALE	63.84	5K	319.2K	76K
Mar 01, 2023	DUNLOP A. SINCLAIR	SALE	65.33	500	32.67K	131.8K
Feb 23, 2023	EISELE JEFFREY	SALE	68.76	1.65K	113.18K	53.88K
Feb 23, 2023	LEWIS KAREN	SALE	68.76	1.1K	75.91K	41.43K
Feb 17, 2023	MACHIELS ALEC	SALE	52.38	1.25K	65.48K	267.64K
Feb 08, 2023	DESCHATELETS PASCAL	SALE	54.45	12K	653.4K	1.01M
Feb 03, 2023	TOWNSEND ADAM J.	SALE	55.85	5K	279.25K	67.93K
Feb 01, 2023	DUNLOP A. SINCLAIR	SALE	52.61	500	26.31K	132.3K
Jan 30, 2023	EISELE JEFFREY	SALE	52.76	883	46.59K	46.47K
Jan 30, 2023	LEWIS KAREN	SALE	52.76	883	46.59K	36.46K
Jan 23, 2023	EISELE JEFFREY	SALE	51.58	4.48K	231.03K	47.72K
Jan 23, 2023	LEWIS KAREN	SALE	51.58	2.96K	152.42K	37.71K
Jan 17, 2023	MACHIELS ALEC	SALE	52.42	1.25K	65.53K	267.64K
Jan 09, 2023	DESCHATELETS PASCAL	SALE	46.08	12K	552.96K	983.78K
Jan 05, 2023	GROSSI FEDERICO	SALE	48.79	2.5K	121.98K	94.88K
Jan 03, 2023	DUNLOP A. SINCLAIR	SALE	50.70	500	25.35K	132.8K
Jan 03, 2023	TOWNSEND ADAM J.	SALE	50.70	5K	253.5K	42.91K
Dec 19, 2022	FRANCOIS CEDRIC	SALE	51.97	3.75K	194.93K	989.58K
Dec 15, 2022	MACHIELS ALEC	SALE	52.35	1.25K	65.44K	263.77K
Dec 08, 2022	DESCHATELETS PASCAL	SALE	47.50	12K	570K	970.28K
Dec 05, 2022	TOWNSEND ADAM J.	SALE	50.38	5K	251.9K	42.91K
Dec 01, 2022	GROSSI FEDERICO	SALE	49.93	2.5K	124.83K	97.38K
Dec 01, 2022	DUNLOP A. SINCLAIR	SALE	49.93	500	24.97K	129.43K
Nov 15, 2022	MACHIELS ALEC	SALE	48.01	1.25K	60.01K	263.77K
Nov 08, 2022	DESCHATELETS PASCAL	SALE	46.47	12K	557.64K	963.78K
Nov 03, 2022	TOWNSEND ADAM J.	SALE	58.54	5K	292.7K	42.91K
Nov 01, 2022	DUNLOP A. SINCLAIR	SALE	60.83	500	30.42K	129.93K
Nov 01, 2022	GROSSI FEDERICO	SALE	60.83	2.5K	152.08K	99.88K
Oct 14, 2022	MACHIELS ALEC	SALE	59.31	1.25K	74.14K	263.77K
Oct 10, 2022	DESCHATELETS PASCAL	SALE	57.50	12K	690K	957.28K
Oct 03, 2022	GROSSI FEDERICO	SALE	66.69	2.5K	166.73K	102.38K
Oct 03, 2022	TOWNSEND ADAM J.	SALE	66.69	5K	333.45K	42.91K
Sep 15, 2022	MACHIELS ALEC	SALE	66.00	1.25K	82.5K	263.77K
Sep 08, 2022	DESCHATELETS PASCAL	SALE	63.98	12K	767.76K	950.78K
Sep 08, 2022	DUNLOP A. SINCLAIR	SALE	65.00	15K	975K	240.68K
Sep 06, 2022	TOWNSEND ADAM J.	SALE	60.38	5K	301.9K	42.91K
Sep 01, 2022	GROSSI FEDERICO	SALE	60.30	2.5K	150.75K	104.88K
Aug 17, 2022	DELONG MARK JEFFREY	SALE	69.50	5K	347.5K	29.25K
Aug 15, 2022	TOWNSEND ADAM J.	SALE	69.00	12.5K	862.5K	42.91K
Aug 15, 2022	MACHIELS ALEC	SALE	67.21	1.25K	84.01K	263.77K
Aug 11, 2022	DELONG MARK JEFFREY	SALE	67.00	5K	335K	29.25K
Aug 11, 2022	TOWNSEND ADAM J.	SALE	67.00	12.5K	837.5K	42.91K
Aug 11, 2022	DUNLOP A. SINCLAIR	SALE	65.63	30K	1.97M	255.68K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES98.44K44

NET SHARES-98.44K44

SHARES HELD8.81M44

% NET SHARES-101.12%0%

Frequently Asked Questions

APLS Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares17.94

Short Percent Of Float24.48

Shares Outstanding125.52M

Shares Float84.23M

Shares Short22.51M

Short Ratio11.85

24.48%

Short % of Float

17.94%

Short % of Shares Outstanding

Market Insider APLS

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

13.86% Percentage of Shares held by All Insiders

103.48% Percentage of Shares held by All Institutions

120.12% Percentage of Float held by Institutions

375

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2024	DEUTSCHE BANK AG\	1.36%	1.61M	94.74M	754.77K	+88.07%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.42%	1.69M	99.35M	59.25K	+3.63%
Mar 31, 2024	BOXER CAPITAL, LLC	1.45%	1.73M	101.45M	0	0
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	1.71%	2.02M	118.95M	-121.39K	-5.66%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.34%	406.48K	23.89M	312.52K	+332.58%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.75%	885.17K	52.03M	0	0
Mar 31, 2024	MORGAN STANLEY	1.38%	1.64M	96.26M	-1.46M	-47.12%
Mar 31, 2024	JENNISON ASSOCIATES LLC	2.73%	3.24M	190.48M	-35.41K	-1.08%
Mar 31, 2024	BLACKROCK INC.	4.63%	5.49M	322.97M	113.34K	+2.11%
Mar 31, 2024	VANGUARD GROUP INC	8.01%	9.51M	558.75M	-49.81K	-0.52%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.88%	4.61M	270.73M	-1.7M	-26.93%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.41%	491.9K	28.91M	-124.38K	-20.18%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.42%	494.69K	29.08M	238.16K	+92.84%
Mar 31, 2024	FMR LLC	1.84%	2.18M	128.07M	86.28K	+4.12%
Mar 31, 2024	JPMORGAN CHASE & CO	1.87%	2.21M	130.16M	-359.82K	-13.98%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.07%	2.46M	144.56M	-1.09K	-0.04%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	2.37%	2.81M	164.99M	0	0
Mar 31, 2024	STATE STREET CORP	2.45%	2.91M	171.02M	-5.89K	-0.20%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.23%	270.58K	15.9M	56	+0.02%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.24%	287.28K	16.89M	135.08K	+88.75%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.22%	260.27K	15.3M	14.71K	+5.99%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.21%	245.56K	14.43M	-81K	-24.80%
Mar 31, 2024	FIDUCIARY TRUST CO	0.2%	240.99K	14.17M	-1.62K	-0.67%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.2%	232.24K	13.65M	232.24K	+100.00%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.19%	226.65K	13.32M	-3.14K	-1.37%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.19%	225K	13.23M	225K	+100.00%
Mar 31, 2024	MACQUARIE GROUP LTD	0.19%	221.65K	13.03M	-361.78K	-62.01%
Mar 31, 2024	ABRDN PLC	0.16%	189.81K	11.16M	20.76K	+12.28%
Mar 31, 2024	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.15%	178.4K	10.49M	78K	+77.68%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.14%	165K	9.7M	90K	+120.00%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	148.8K	8.75M	5.68K	+3.97%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.12%	145.83K	8.57M	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.12%	145.04K	8.53M	12.47K	+9.41%
Mar 31, 2024	SWISS NATIONAL BANK	0.12%	140.3K	8.25M	-22.1K	-13.61%
Mar 31, 2024	SENATOR INVESTMENT GROUP LP	0.12%	140K	8.23M	140K	+100.00%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.11%	132.94K	7.83M	-336.95K	-71.71%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	123.33K	7.25M	17.33K	+16.35%
Mar 31, 2024	RHUMBLINE ADVISERS	0.1%	120.92K	7.11M	-12.67K	-9.48%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.1%	115.45K	6.79M	56.18K	+94.78%
Mar 31, 2024	UBS GROUP AG	0.09%	111.29K	6.54M	16.26K	+17.11%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.08%	94.61K	5.56M	8.18K	+9.46%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.08%	92.66K	5.45M	92.66K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.08%	89.7K	5.27M	89.7K	+100.00%
Mar 31, 2024	LISANTI CAPITAL GROWTH, LLC	0.08%	89.21K	5.24M	42.91K	+92.66%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	12.69%	15.06M	885.11M	-1.39M	-8.44%
Mar 31, 2024	ECOR1 CAPITAL, LLC	9.57%	11.36M	667.59M	184.36K	+1.65%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	9.36%	11.11M	653.11M	0	0
Mar 31, 2024	CITADEL ADVISORS LLC	0.25%	293K	17.22M	-115.4K	-28.26%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.27%	319.48K	18.78M	8.89K	+2.86%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.27%	322.92K	18.98M	-49.33K	-13.25%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.27%	325.93K	19.16M	-14.58K	-4.28%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.27%	321.8K	18.92M	-623.9K	-65.97%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	0.34%	400K	23.51M	-225K	-36.00%
Mar 31, 2024	NORTHERN TRUST CORP	0.37%	440.46K	25.89M	-8.27K	-1.84%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.39%	459.4K	27M	-23.92K	-4.95%
Mar 31, 2024	BELLEVUE GROUP AG	0.4%	473.92K	27.86M	-347.89K	-42.33%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.42%	503.04K	29.57M	21.54K	+4.47%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	0.45%	531.36K	31.23M	-34.22K	-6.05%
Mar 31, 2024	IRON TRIANGLE PARTNERS LP	0.46%	550K	32.33M	550K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	584.93K	34.38M	247.42K	+73.31%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.61%	723.44K	42.52M	289.11K	+66.56%
Mar 31, 2024	INVESCO LTD.	0.64%	762.12K	44.8M	243.28K	+46.89%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.66%	785.4K	46.17M	772.87K	+6,169.63%
Mar 31, 2024	LOGOS GLOBAL MANAGEMENT LP	0.67%	800K	47.02M	-150K	-15.79%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.71%	845.53K	50.49M	399.53K	+89.58%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.78%	924.56K	54.35M	20.15K	+2.23%
Mar 31, 2024	FIERA CAPITAL CORP	0.8%	948.44K	55.75M	29.35K	+3.19%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.84%	1M	58.78M	1M	+100.00%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	0.89%	1.05M	61.98M	1K	+0.09%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.9%	1.07M	63.03M	-271.33K	-20.18%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.09%	1.3M	76.28M	375.6K	+40.73%
Mar 31, 2024	ARTAL GROUP S.A.	1.11%	1.32M	77.31M	-106.06K	-7.46%
Dec 31, 2023	EAGLE ASSET MANAGEMENT INC	0.37%	446K	26.7M	-3.97K	-0.88%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	13.67%	16.45M	984.42M	16.45M	+100.00%
Dec 31, 2023	ECOR1 CAPITAL, LLC	9.29%	11.17M	668.82M	273.21K	+2.51%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	9.24%	11.11M	665.11M	0	0
Dec 31, 2023	VANGUARD GROUP INC	7.94%	9.56M	572M	85.7K	+0.91%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	5.24%	6.3M	377.33M	-215.89K	-3.31%
Dec 31, 2023	BLACKROCK INC.	4.47%	5.38M	322.12M	108.51K	+2.06%
Dec 31, 2023	JENNISON ASSOCIATES LLC	2.72%	3.28M	196.1M	-266.29K	-7.52%
Dec 31, 2023	MORGAN STANLEY	2.57%	3.1M	185.39M	1.49M	+92.49%
Dec 31, 2023	STATE STREET CORP	2.42%	2.92M	174.52M	-322.69K	-9.97%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	2.33%	2.81M	168.03M	-323.02K	-10.32%
Dec 31, 2023	JPMORGAN CHASE & CO	2.14%	2.57M	154.09M	356.39K	+16.07%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.05%	2.46M	147.28M	677.1K	+37.97%
Dec 31, 2023	ASSENAGON ASSET MANAGEMENT S.A.	1.78%	2.15M	128.4M	1.12M	+109.57%
Dec 31, 2023	FMR LLC	1.74%	2.09M	125.25M	-167.3K	-7.40%
Dec 31, 2023	BOXER CAPITAL, LLC	1.43%	1.73M	103.32M	0	0
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.36%	1.63M	97.63M	75.82K	+4.88%
Dec 31, 2023	ARTAL GROUP S.A.	1.18%	1.42M	85.08M	-243.23K	-14.61%
Dec 31, 2023		1.12%	1.34M	80.49M	610.41K	+83.15%
Dec 31, 2023	NORGES BANK	0.79%	946.21K	56.64M	946.21K	+100.00%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	0.88%	1.05M	63.06M	-435	-0.04%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	0.79%	950K	56.87M	200K	+26.67%
Dec 31, 2023	ORBIMED ADVISORS LLC	0.77%	922.2K	55.2M	-338.3K	-26.84%
Dec 31, 2023	FIERA CAPITAL CORP	0.76%	919.09K	55.02M	-600	-0.07%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.75%	904.41K	54.14M	25.05K	+2.85%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.74%	885.17K	52.99M	271.12K	+44.15%
Dec 31, 2023	DEUTSCHE BANK AG\	0.71%	857K	51.3M	532.71K	+164.27%
Dec 31, 2023	BELLEVUE GROUP AG	0.68%	821.8K	49.19M	27.96K	+3.52%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	0.52%	625K	37.41M	-1.38M	-68.75%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.51%	616.27K	36.89M	-122.24K	-16.55%
Dec 31, 2023	MACQUARIE GROUP LTD	0.49%	583.43K	34.92M	-493.12K	-45.81%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	0.47%	565.58K	33.86M	213.19K	+60.50%
Dec 31, 2023	INVESCO LTD.	0.43%	518.84K	31.06M	-21.84K	-4.04%
Dec 31, 2023	PORTMAN SQUARE CAPITAL LLP	0.42%	500K	29.93M	292.5K	+140.96%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.4%	483.32K	28.93M	112.47K	+30.33%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.4%	481.5K	28.82M	300.18K	+165.55%
Dec 31, 2023	BANK OF MONTREAL /CAN/	0.39%	469.88K	29.61M	37.91K	+8.78%
Dec 31, 2023	NORTHERN TRUST CORP	0.37%	448.73K	26.86M	-1.7K	-0.38%
Dec 31, 2023	JANE STREET GROUP, LLC	0.36%	434.7K	26.02M	161.48K	+59.10%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.36%	434.34K	26M	-270.62K	-38.39%
Dec 31, 2023	CITADEL ADVISORS LLC	0.33%	394.9K	23.64M	-285K	-41.92%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.28%	336.4K	20.14M	-250.8K	-42.71%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.31%	372.26K	22.28M	11.97K	+3.32%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.28%	340.51K	20.38M	-62.44K	-15.50%
Dec 31, 2023	CANDRIAM S.C.A.	0.28%	337.51K	20.2M	11K	+3.37%
Dec 31, 2023	PRUDENTIAL FINANCIAL INC	0.27%	326.56K	19.55M	23K	+7.58%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.26%	310.58K	18.59M	-21.21K	-6.39%
Sep 30, 2023	AVORO CAPITAL ADVISORS LLC	9.31%	11.11M	-	0	0
Sep 30, 2023	PORTMAN SQUARE CAPITAL LLP	0.17%	207.5K	-	207.5K	+100.00%
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.18%	214.16K	-	121.89K	+132.11%
Sep 30, 2023	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.18%	215K	-	25K	+13.16%
Sep 30, 2023	GROUP ONE TRADING, L.P.	0.19%	226.68K	-	207.87K	+1,104.61%
Sep 30, 2023	BNP PARIBAS ARBITRAGE, SNC	0.2%	236.36K	-	177.69K	+302.92%
Sep 30, 2023	FIDUCIARY TRUST CO	0.22%	265.21K	-	-8.71K	-3.18%
Sep 30, 2023	JANE STREET GROUP, LLC	0.23%	273.23K	-	-207.86K	-43.21%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.23%	273.51K	-	11.12K	+4.24%
Sep 30, 2023	AMUNDI	0.23%	278.96K	-	242.86K	+672.67%
Sep 30, 2023	BANK OF NOVA SCOTIA	0.25%	293.31K	-	288.69K	+6,248.59%
Sep 30, 2023	PRUDENTIAL FINANCIAL INC	0.25%	303.56K	-	126.48K	+71.43%
Sep 30, 2023	DEUTSCHE BANK AG\	0.27%	324.29K	-	-154.07K	-32.21%
Sep 30, 2023	CANDRIAM S.C.A.	0.27%	326.51K	-	0	0
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.28%	331.79K	-	-303.1K	-47.74%
Sep 30, 2023	BARCLAYS PLC	0.29%	342.89K	-	30.66K	+9.82%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.3%	352.39K	-	211.31K	+149.79%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.3%	360.29K	-	3K	+0.84%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.31%	370.86K	-	-107.87K	-22.53%
Sep 30, 2023	FIRST TRUST ADVISORS LP	0.33%	398.14K	-	320.85K	+415.12%
Sep 30, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.34%	402.94K	-	101.95K	+33.87%
Sep 30, 2023	BANK OF MONTREAL /CAN/	0.36%	431.97K	-	354.05K	+454.34%
Sep 30, 2023	EAGLE ASSET MANAGEMENT INC	0.38%	449.97K	-	-962	-0.21%
Sep 30, 2023	NORTHERN TRUST CORP	0.38%	450.43K	-	-401.84K	-47.15%
Sep 30, 2023	INVESCO LTD.	0.45%	540.68K	-	-611.72K	-53.08%
Sep 30, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	0.46%	548.87K	-	-47.36K	-7.94%
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.49%	587.2K	-	421.7K	+254.80%
Sep 30, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.51%	614.04K	-	614.04K	+100.00%
Sep 30, 2023		0.62%	734.15K	-	734.15K	+100.00%
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.62%	738.51K	-	337.55K	+84.19%
Sep 30, 2023	BELLEVUE GROUP AG	0.67%	793.84K	-	275.35K	+53.10%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.74%	879.36K	-	50.84K	+6.14%
Sep 30, 2023	FIERA CAPITAL CORP	0.77%	919.69K	-	391.77K	+74.21%
Sep 30, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.86%	1.02M	-	524.8K	+105.23%
Sep 30, 2023	POLAR CAPITAL HOLDINGS PLC	0.88%	1.05M	-	588.88K	+126.64%
Sep 30, 2023	ORBIMED ADVISORS LLC	1.06%	1.26M	-	350.3K	+38.49%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.3%	1.55M	-	56.44K	+3.77%
Sep 30, 2023	MORGAN STANLEY	1.35%	1.61M	-	852.33K	+112.64%
Sep 30, 2023	ARTAL GROUP S.A.	1.4%	1.66M	-	614.51K	+58.52%
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	1.68%	2M	-	690K	+52.67%
Sep 30, 2023	SLATE PATH CAPITAL LP	1.73%	2.07M	-	2.07M	+100.00%
Sep 30, 2023	FMR LLC	1.89%	2.26M	-	-1.97M	-46.52%
Sep 30, 2023	JENNISON ASSOCIATES LLC	2.97%	3.54M	-	1.57M	+79.75%
Sep 30, 2023	BLACKROCK INC.	4.42%	5.27M	-	-474.88K	-8.26%
Sep 30, 2023	ECOR1 CAPITAL, LLC	9.14%	10.9M	-	5.45M	+99.94%

APLS Insiders

Insiders	Designation	Shares Held
DESCHATELETS PASCAL	Chief Scientific Officer	1.15M
FRANCOIS CEDRIC	Chief Executive Officer	415.7K
MACHIELS ALEC	director	367.42K
WATSON DAVID O.	General Counsel	138.73K
SULLIVAN TIMOTHY EUGENE	Chief Financial Officer	128.67K
DUNLOP A. SINCLAIR	director	100K
GROSSI FEDERICO	Chief Medical Officer	94.88K
TOWNSEND ADAM J.	Chief Commercial Officer	84.05K
DELONG MARK JEFFREY	Chief Business & Strat Officer	83.95K
NICHOLSON NUR	Chief Technical Officer	83.66K
LEWIS KAREN	Chief People Officer	70.25K
SCHEIBLER LUKAS	Chief Research Officer	68.3K
EISELE JEFFREY	Chief Development Officer	55.31K
BAUMAL CAROLINE	Chief Medical Officer	53.71K
CHOPAS JAMES GEORGE	VP/Chief Accounting Officer	47.96K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 17, 2025	CHOPAS JAMES GEORGE	SALE	24.82	183	4.54K	47.96K
Mar 05, 2025	WATSON DAVID O.	SALE	25.10	5.57K	139.79K	138.73K
Feb 11, 2025	DELONG MARK JEFFREY	SALE	28.54	363	10.36K	83.95K
Jan 29, 2025	TOWNSEND ADAM J.	SALE	29.52	695	20.52K	84.05K
Jan 29, 2025	DELONG MARK JEFFREY	SALE	29.52	365	10.78K	84.31K
Jan 29, 2025	FRANCOIS CEDRIC	SALE	29.52	2.82K	83.37K	415.7K
Jan 29, 2025	DESCHATELETS PASCAL	SALE	29.52	826	24.39K	1.15M
Jan 29, 2025	EISELE JEFFREY	SALE	29.52	278	8.21K	55.31K
Jan 29, 2025	NICHOLSON NUR	SALE	29.52	825	24.36K	83.66K
Jan 29, 2025	LEWIS KAREN	SALE	29.52	364	10.75K	70.25K
Jan 29, 2025	SULLIVAN TIMOTHY EUGENE	SALE	29.52	546	16.12K	128.67K
Jan 29, 2025	WATSON DAVID O.	SALE	29.52	695	20.52K	144.3K
Jan 22, 2025	LEWIS KAREN	SALE	30.43	1.75K	53.28K	70.62K
Jan 22, 2025	SULLIVAN TIMOTHY EUGENE	SALE	30.43	3.09K	93.95K	129.21K
Jan 22, 2025	DESCHATELETS PASCAL	SALE	30.43	3.95K	120.12K	1.15M
Jan 22, 2025	EISELE JEFFREY	SALE	30.43	1.29K	39.28K	55.59K
Jan 22, 2025	TOWNSEND ADAM J.	SALE	30.43	3.32K	101.1K	84.75K
Jan 22, 2025	WATSON DAVID O.	SALE	30.43	3.32K	101.1K	144.99K
Jan 22, 2025	CHOPAS JAMES GEORGE	SALE	30.43	1.1K	33.35K	48.14K
Jan 22, 2025	DELONG MARK JEFFREY	SALE	30.43	1.4K	42.47K	84.67K
Jan 22, 2025	FRANCOIS CEDRIC	SALE	30.43	13.55K	412.3K	418.52K
Jan 22, 2025	NICHOLSON NUR	SALE	30.43	3.95K	120.12K	84.49K
Jan 17, 2025	LEWIS KAREN	SALE	29.96	1.24K	37.18K	43.86K
Jan 17, 2025	NICHOLSON NUR	SALE	29.96	2.15K	64.26K	52.01K
Jan 17, 2025	BAUMAL CAROLINE	SALE	29.96	1.85K	55.51K	53.71K
Jan 17, 2025	CHOPAS JAMES GEORGE	SALE	29.96	715	21.42K	36.64K
Jan 17, 2025	SULLIVAN TIMOTHY EUGENE	SALE	29.96	1.73K	51.83K	86.37K
Jan 17, 2025	TOWNSEND ADAM J.	SALE	29.96	2.2K	65.94K	88.07K
Jan 17, 2025	WATSON DAVID O.	SALE	29.96	2.2K	65.94K	105.56K
Jan 17, 2025	DELONG MARK JEFFREY	SALE	29.96	1.24K	37K	57.56K
Jan 17, 2025	DESCHATELETS PASCAL	SALE	29.96	750	22.47K	1.14M
Jan 17, 2025	FRANCOIS CEDRIC	SALE	29.96	6.01K	179.96K	301.41K
Jan 13, 2025	DESCHATELETS PASCAL	SALE	28.70	2.29K	65.67K	1.14M
Jan 13, 2025	CHOPAS JAMES GEORGE	SALE	28.70	783	22.47K	37.36K
Jan 13, 2025	DELONG MARK JEFFREY	SALE	28.70	1.6K	45.89K	58.8K
Jan 13, 2025	EISELE JEFFREY	SALE	28.70	264	7.58K	56.88K
Jan 13, 2025	SULLIVAN TIMOTHY EUGENE	SALE	28.70	2.17K	62.28K	88.1K
Jan 13, 2025	TOWNSEND ADAM J.	SALE	28.70	2.69K	77.07K	90.27K
Jan 13, 2025	WATSON DAVID O.	SALE	28.70	4.97K	142.51K	107.76K
Jan 13, 2025	FRANCOIS CEDRIC	SALE	28.70	6.25K	179.3K	307.42K
Jan 13, 2025	LEWIS KAREN	SALE	28.70	1.6K	45.89K	45.1K
Jan 13, 2025	NICHOLSON NUR	SALE	28.70	2.63K	75.54K	54.16K
Jan 06, 2025	BAUMAL CAROLINE	SALE	33.81	2.82K	95.21K	55.56K
Dec 23, 2024	EISELE JEFFREY	SALE	33.09	63	2.08K	57.15K
Sep 16, 2024	CHOPAS JAMES GEORGE	SALE	36.21	192	6.95K	38.14K
Sep 16, 2024	DUNLOP A. SINCLAIR	SALE	36.79	7.52K	276.81K	100K
Sep 03, 2024	CHOPAS JAMES GEORGE	SALE	39.49	550	21.72K	38.33K
Jun 21, 2024	DUNLOP A. SINCLAIR	SALE	39.63	1.7K	67.17K	137K
May 08, 2024	DESCHATELETS PASCAL	SALE	44.02	100	4.4K	1.12M
Apr 08, 2024	DESCHATELETS PASCAL	SALE	54.92	4.73K	259.64K	1.12M
Apr 01, 2024	SULLIVAN TIMOTHY EUGENE	SALE	58.66	4K	234.64K	93.34K
Mar 19, 2024	DUNLOP A. SINCLAIR	SALE	57.18	18.68K	1.07M	174K
Mar 18, 2024	DELONG MARK JEFFREY	SALE	56.90	9.91K	564.05K	54.69K
Mar 15, 2024	CHOPAS JAMES GEORGE	SALE	56.46	184	10.39K	38.88K
Mar 13, 2024	NICHOLSON NUR	SALE	58.13	3.45K	200.68K	56.29K
Mar 08, 2024	DESCHATELETS PASCAL	SALE	63.35	100	6.34K	1.12M
Mar 01, 2024	SULLIVAN TIMOTHY EUGENE	SALE	63.95	2K	127.9K	93.34K
Mar 01, 2024	FRANCOIS CEDRIC	SALE	65.68	413	27.13K	313.66K
Feb 12, 2024	SULLIVAN TIMOTHY EUGENE	SALE	67.77	1.43K	96.97K	93.34K
Feb 12, 2024	DELONG MARK JEFFREY	SALE	67.77	597	40.46K	64.61K
Feb 12, 2024	DESCHATELETS PASCAL	SALE	67.77	1.15K	77.8K	1.12M
Feb 12, 2024	WATSON DAVID O.	SALE	67.77	781	52.93K	103.39K
Feb 12, 2024	FRANCOIS CEDRIC	SALE	67.77	3.96K	268.49K	313.66K
Feb 12, 2024	TOWNSEND ADAM J.	SALE	67.77	1.15K	77.8K	92.45K
Jan 30, 2024	EISELE JEFFREY	SALE	65.53	971	63.63K	57.21K
Jan 30, 2024	LEWIS KAREN	SALE	65.53	883	57.86K	46.39K
Jan 29, 2024	NICHOLSON NUR	SALE	64.14	835	53.56K	67.51K
Jan 29, 2024	DESCHATELETS PASCAL	SALE	64.14	874	56.06K	1.12M
Jan 29, 2024	DELONG MARK JEFFREY	SALE	64.14	367	23.54K	65.2K
Jan 29, 2024	LEWIS KAREN	SALE	64.14	367	23.54K	47.27K
Jan 29, 2024	TOWNSEND ADAM J.	SALE	64.14	906	58.11K	93.6K
Jan 29, 2024	SULLIVAN TIMOTHY EUGENE	SALE	64.14	906	58.11K	94.77K
Jan 29, 2024	WATSON DAVID O.	SALE	64.14	906	58.11K	104.17K
Jan 29, 2024	EISELE JEFFREY	SALE	64.14	279	17.89K	58.18K
Jan 29, 2024	FRANCOIS CEDRIC	SALE	64.14	2.84K	182.34K	317.62K
Jan 23, 2024	EISELE JEFFREY	SALE	63.69	7.38K	469.9K	58.46K
Jan 23, 2024	LEWIS KAREN	SALE	63.69	4.29K	272.98K	47.64K
Jan 22, 2024	FRANCOIS CEDRIC	SALE	65.00	13.43K	872.96K	320.47K
Jan 22, 2024	DELONG MARK JEFFREY	SALE	65.00	1.38K	89.95K	65.57K
Jan 22, 2024	WATSON DAVID O.	SALE	65.00	4.18K	271.94K	105.08K
Jan 22, 2024	TOWNSEND ADAM J.	SALE	65.00	3.41K	221.83K	94.51K
Jan 22, 2024	SULLIVAN TIMOTHY EUGENE	SALE	65.00	3.55K	230.8K	95.68K
Jan 22, 2024	EISELE JEFFREY	SALE	65.00	1.61K	104.45K	65.84K
Jan 22, 2024	CHOPAS JAMES GEORGE	SALE	65.00	1.06K	68.96K	39.07K
Jan 22, 2024	NICHOLSON NUR	SALE	65.00	2.59K	168.53K	68.34K
Jan 22, 2024	LEWIS KAREN	SALE	65.00	1.74K	112.96K	51.92K
Jan 22, 2024	DESCHATELETS PASCAL	SALE	65.00	3.91K	254.33K	1.12M
Jan 17, 2024	EISELE JEFFREY	SALE	65.58	5.21K	341.48K	67.44K
Jan 17, 2024	LEWIS KAREN	SALE	65.58	3.28K	214.84K	53.66K
Jan 16, 2024	EISELE JEFFREY	SALE	66.81	438	29.26K	72.65K
Jan 16, 2024	DELONG MARK JEFFREY	SALE	66.81	1.63K	108.96K	66.95K
Jan 16, 2024	SULLIVAN TIMOTHY EUGENE	SALE	66.81	2.24K	149.32K	99.23K
Jan 16, 2024	WATSON DAVID O.	SALE	66.81	4.24K	283.27K	109.26K
Jan 16, 2024	DESCHATELETS PASCAL	SALE	66.81	1.63K	109.03K	1.12M
Jan 16, 2024	LEWIS KAREN	SALE	66.81	1.63K	109.03K	56.94K
Jan 16, 2024	NICHOLSON NUR	SALE	66.81	1.86K	124.06K	70.94K
Jan 16, 2024	TOWNSEND ADAM J.	SALE	66.81	2.24K	149.32K	97.92K
Jan 16, 2024	CHOPAS JAMES GEORGE	SALE	66.81	864	57.72K	40.13K
Jan 16, 2024	FRANCOIS CEDRIC	SALE	66.81	7.85K	524.51K	333.9K
Jan 04, 2024	BAUMAL CAROLINE	SALE	60.05	2.75K	165.21K	32.93K
Dec 27, 2023	EISELE JEFFREY	SALE	60.23	235	14.15K	53.58K
Dec 26, 2023	EISELE JEFFREY	SALE	57.86	68	3.93K	53.82K
Dec 19, 2023	WATSON DAVID O.	SALE	57.38	2.3K	131.98K	89.75K
Dec 01, 2023	DUNLOP A. SINCLAIR	SALE	61.13	24K	1.47M	192.68K
Dec 01, 2023	SCHEIBLER LUKAS	SALE	60.00	10K	600K	68.3K
Dec 01, 2023	TOWNSEND ADAM J.	SALE	61.31	42.44K	2.6M	76.41K
Nov 30, 2023	SULLIVAN TIMOTHY EUGENE	SALE	54.79	300	16.44K	77.71K
Nov 21, 2023	FRANCOIS CEDRIC	SALE	48.80	5K	244K	269.66K
Nov 17, 2023	DUNLOP A. SINCLAIR	SALE	49.99	8.89K	444.62K	122.4K
Nov 17, 2023	MACHIELS ALEC	SALE	47.74	1.25K	59.68K	367.42K
Nov 08, 2023	DESCHATELETS PASCAL	SALE	47.27	12K	567.24K	1.07M
Oct 23, 2023	DELONG MARK JEFFREY	SALE	46.04	131	6.03K	51.62K
Oct 23, 2023	CHOPAS JAMES GEORGE	SALE	46.04	132	6.08K	32.68K
Oct 17, 2023	MACHIELS ALEC	SALE	48.50	1.25K	60.63K	367.42K
Oct 17, 2023	DUNLOP A. SINCLAIR	SALE	49.00	24K	1.18M	216.68K
Oct 09, 2023	DESCHATELETS PASCAL	SALE	40.38	12K	484.56K	1.07M
Sep 18, 2023	MACHIELS ALEC	SALE	45.00	1.25K	56.25K	367.42K
Sep 18, 2023	NICHOLSON NUR	SALE	46.15	10.63K	490.59K	53.28K
Sep 15, 2023	MACHIELS ALEC	SALE	45.34	1.25K	56.68K	367.42K
Sep 08, 2023	DESCHATELETS PASCAL	SALE	42.87	12K	514.44K	1.06M
Sep 06, 2023	SCHEIBLER LUKAS	SALE	43.01	1.76K	75.53K	68.3K
Sep 01, 2023	FRANCOIS CEDRIC	SALE	42.44	10.28K	436.45K	424.66K
Aug 31, 2023	CHOPAS JAMES GEORGE	SALE	41.23	551	22.72K	30.31K
Aug 08, 2023	DESCHATELETS PASCAL	SALE	23.66	12K	283.92K	1.05M
Jul 17, 2023	MACHIELS ALEC	SALE	64.79	1.25K	80.99K	267.64K
Jul 10, 2023	DESCHATELETS PASCAL	SALE	84.55	12K	1.01M	1.05M
Jul 03, 2023	SULLIVAN TIMOTHY EUGENE	SALE	91.10	300	27.33K	77.71K
Jul 03, 2023	WATSON DAVID O.	SALE	89.98	8.51K	765.73K	85.75K
Jun 20, 2023	MACHIELS ALEC	SALE	88.41	1.25K	110.51K	267.64K
Jun 08, 2023	DESCHATELETS PASCAL	SALE	91.35	12K	1.1M	1.04M
Jun 05, 2023	SULLIVAN TIMOTHY EUGENE	SALE	90.60	1.6K	144.97K	145.89K
Jun 01, 2023	LEWIS KAREN	SALE	86.00	5K	430K	41.5K
May 17, 2023	MACHIELS ALEC	SALE	88.66	1.25K	110.83K	267.64K
May 16, 2023	FRANCOIS CEDRIC	SALE	83.17	934	77.68K	303.72K
May 08, 2023	DESCHATELETS PASCAL	SALE	92.39	12K	1.11M	1.03M
May 03, 2023	TOWNSEND ADAM J.	SALE	82.71	5K	413.55K	76K
Apr 18, 2023	FRANCOIS CEDRIC	SALE	82.02	30K	2.46M	637.6K
Apr 17, 2023	MACHIELS ALEC	SALE	81.05	1.25K	101.31K	267.64K
Apr 10, 2023	DESCHATELETS PASCAL	SALE	78.21	12K	938.52K	1.03M
Apr 03, 2023	TOWNSEND ADAM J.	SALE	74.05	5K	370.25K	76K
Apr 03, 2023	LEWIS KAREN	SALE	75.00	5K	375K	41.43K
Apr 03, 2023	DUNLOP A. SINCLAIR	SALE	74.05	500	37.03K	131.3K
Mar 21, 2023	FRANCOIS CEDRIC	SALE	62.74	30K	1.88M	1.14M
Mar 17, 2023	MACHIELS ALEC	SALE	64.03	1.25K	80.04K	267.64K
Mar 08, 2023	DESCHATELETS PASCAL	SALE	63.79	12K	765.48K	1.02M
Mar 03, 2023	TOWNSEND ADAM J.	SALE	63.84	5K	319.2K	76K
Mar 01, 2023	DUNLOP A. SINCLAIR	SALE	65.33	500	32.67K	131.8K
Feb 23, 2023	EISELE JEFFREY	SALE	68.76	1.65K	113.18K	53.88K
Feb 23, 2023	LEWIS KAREN	SALE	68.76	1.1K	75.91K	41.43K
Feb 17, 2023	MACHIELS ALEC	SALE	52.38	1.25K	65.48K	267.64K
Feb 08, 2023	DESCHATELETS PASCAL	SALE	54.45	12K	653.4K	1.01M
Feb 03, 2023	TOWNSEND ADAM J.	SALE	55.85	5K	279.25K	67.93K
Feb 01, 2023	DUNLOP A. SINCLAIR	SALE	52.61	500	26.31K	132.3K
Jan 30, 2023	EISELE JEFFREY	SALE	52.76	883	46.59K	46.47K
Jan 30, 2023	LEWIS KAREN	SALE	52.76	883	46.59K	36.46K
Jan 23, 2023	EISELE JEFFREY	SALE	51.58	4.48K	231.03K	47.72K
Jan 23, 2023	LEWIS KAREN	SALE	51.58	2.96K	152.42K	37.71K
Jan 17, 2023	MACHIELS ALEC	SALE	52.42	1.25K	65.53K	267.64K
Jan 09, 2023	DESCHATELETS PASCAL	SALE	46.08	12K	552.96K	983.78K
Jan 05, 2023	GROSSI FEDERICO	SALE	48.79	2.5K	121.98K	94.88K
Jan 03, 2023	DUNLOP A. SINCLAIR	SALE	50.70	500	25.35K	132.8K
Jan 03, 2023	TOWNSEND ADAM J.	SALE	50.70	5K	253.5K	42.91K
Dec 19, 2022	FRANCOIS CEDRIC	SALE	51.97	3.75K	194.93K	989.58K
Dec 15, 2022	MACHIELS ALEC	SALE	52.35	1.25K	65.44K	263.77K
Dec 08, 2022	DESCHATELETS PASCAL	SALE	47.50	12K	570K	970.28K
Dec 05, 2022	TOWNSEND ADAM J.	SALE	50.38	5K	251.9K	42.91K
Dec 01, 2022	GROSSI FEDERICO	SALE	49.93	2.5K	124.83K	97.38K
Dec 01, 2022	DUNLOP A. SINCLAIR	SALE	49.93	500	24.97K	129.43K
Nov 15, 2022	MACHIELS ALEC	SALE	48.01	1.25K	60.01K	263.77K
Nov 08, 2022	DESCHATELETS PASCAL	SALE	46.47	12K	557.64K	963.78K
Nov 03, 2022	TOWNSEND ADAM J.	SALE	58.54	5K	292.7K	42.91K
Nov 01, 2022	DUNLOP A. SINCLAIR	SALE	60.83	500	30.42K	129.93K
Nov 01, 2022	GROSSI FEDERICO	SALE	60.83	2.5K	152.08K	99.88K
Oct 14, 2022	MACHIELS ALEC	SALE	59.31	1.25K	74.14K	263.77K
Oct 10, 2022	DESCHATELETS PASCAL	SALE	57.50	12K	690K	957.28K
Oct 03, 2022	GROSSI FEDERICO	SALE	66.69	2.5K	166.73K	102.38K
Oct 03, 2022	TOWNSEND ADAM J.	SALE	66.69	5K	333.45K	42.91K
Sep 15, 2022	MACHIELS ALEC	SALE	66.00	1.25K	82.5K	263.77K
Sep 08, 2022	DESCHATELETS PASCAL	SALE	63.98	12K	767.76K	950.78K
Sep 08, 2022	DUNLOP A. SINCLAIR	SALE	65.00	15K	975K	240.68K
Sep 06, 2022	TOWNSEND ADAM J.	SALE	60.38	5K	301.9K	42.91K
Sep 01, 2022	GROSSI FEDERICO	SALE	60.30	2.5K	150.75K	104.88K
Aug 17, 2022	DELONG MARK JEFFREY	SALE	69.50	5K	347.5K	29.25K
Aug 15, 2022	TOWNSEND ADAM J.	SALE	69.00	12.5K	862.5K	42.91K
Aug 15, 2022	MACHIELS ALEC	SALE	67.21	1.25K	84.01K	263.77K
Aug 11, 2022	DELONG MARK JEFFREY	SALE	67.00	5K	335K	29.25K
Aug 11, 2022	TOWNSEND ADAM J.	SALE	67.00	12.5K	837.5K	42.91K
Aug 11, 2022	DUNLOP A. SINCLAIR	SALE	65.63	30K	1.97M	255.68K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES98.44K44

NET SHARES-98.44K44

SHARES HELD8.81M44

% NET SHARES-101.12%0%

APLS Stock Ownership Breakdown

Apellis Pharmaceuticals, Inc.

APLS Stock Outstanding Shares

Market Insider APLS

Institutional Ownership

APLS Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

APLS Stock Outstanding Shares

Market Insider APLS

Institutional Ownership

APLS Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions