| 2024-03-31 | COMMONWEALTH EQUITY SERVICES, LLC | 0.01% | 6.5K | 209K | 6.5K | +100.00% |
| 2024-03-31 | DAIWA SECURITIES GROUP INC. | 0% | 51 | 2K | 0 | 0 |
| 2024-03-31 | BOGART WEALTH, LLC | 0% | 49 | 1.58K | 0 | 0 |
| 2024-03-31 | PRINCIPAL SECURITIES, INC. | 0% | 48 | 1.55K | 48 | +100.00% |
| 2024-03-31 | NEWEDGE ADVISORS, LLC | 0% | 6 | 193 | 0 | 0 |
| 2024-03-31 | HARBOR INVESTMENT ADVISORY, LLC | 0% | 4 | 129 | 4 | +100.00% |
| 2024-03-31 | ECOR1 CAPITAL, LLC | 8.74% | 5.76M | 185.35M | 0 | 0 |
| 2024-03-31 | FMR LLC | 6.34% | 4.17M | 134.42M | -59.29K | -1.40% |
| 2024-03-31 | PRIMECAP MANAGEMENT CO/CA/ | 1.09% | 715.24K | 23.03M | 36.36K | +5.36% |
| 2024-03-31 | BLACKROCK INC. | 0.79% | 519.29K | 16.72M | 56.03K | +12.09% |
| 2024-03-31 | FINEPOINT CAPITAL LP | 0.76% | 503.76K | 16.22M | 45.1K | +9.83% |
| 2024-03-31 | STONEPINE CAPITAL MANAGEMENT, LLC | 0.6% | 393.63K | 12.68M | 131.76K | +50.32% |
| 2024-03-31 | BVF INC/IL | 2.83% | 1.86M | 60.01M | -51.3K | -2.68% |
| 2024-03-31 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 2.14% | 1.41M | 45.43M | 788.89K | +126.81% |
| 2024-03-31 | PROSIGHT MANAGEMENT, LP | 1.41% | 931.51K | 29.99M | 104.22K | +12.60% |
| 2024-03-31 | SEGALL BRYANT & HAMILL, LLC | 1.32% | 868.04K | 27.95M | -6.69K | -0.76% |
| 2024-03-31 | WELLINGTON MANAGEMENT GROUP LLP | 0.72% | 474.88K | 15.29M | -20.33K | -4.11% |
| 2024-03-31 | HUDSON BAY CAPITAL MANAGEMENT LP | 0.66% | 432.4K | 13.92M | 100.4K | +30.24% |
| 2024-03-31 | NEWTYN MANAGEMENT, LLC | 0.56% | 366K | 11.79M | 147.91K | +67.82% |
| 2024-03-31 | MILLENNIUM MANAGEMENT LLC | 0.49% | 324.55K | 10.45M | 261.99K | +418.82% |
| 2024-03-31 | RENAISSANCE TECHNOLOGIES LLC | 0.4% | 266.5K | 8.58M | 3.3K | +1.25% |
| 2024-03-31 | DME CAPITAL MANAGEMENT, LP | 0.24% | 159.83K | 5.15M | 159.83K | +100.00% |
| 2024-03-31 | DAFNA CAPITAL MANAGEMENT LLC | 0.2% | 130.18K | 4.19M | 0 | 0 |
| 2024-03-31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.01% | 8.28K | 266.75K | -43.56K | -84.02% |
| 2024-03-31 | AMERICAN CENTURY COMPANIES INC | 0.04% | 23.71K | 763.49K | 240 | +1.02% |
| 2024-03-31 | MORGAN STANLEY | 0.04% | 23.66K | 761.92K | -87.67K | -78.75% |
| 2024-03-31 | TWO SIGMA INVESTMENTS, LP | 0.03% | 22.71K | 731.39K | 12.59K | +124.31% |
| 2024-03-31 | MOODY NATIONAL BANK TRUST DIVISION | 0.03% | 22.52K | 725.08K | 0 | 0 |
| 2024-03-31 | CUBIST SYSTEMATIC STRATEGIES, LLC | 0.03% | 20.09K | 646.83K | -25.32K | -55.76% |
| 2024-03-31 | MONACO ASSET MANAGEMENT SAM | 0.03% | 16.74K | 539.16K | 10K | +148.28% |
| 2024-03-31 | ACADIAN ASSET MANAGEMENT LLC | 0.02% | 15.19K | 488K | 2.37K | +18.46% |
| 2024-03-31 | VESTAL POINT CAPITAL, LP | 0.2% | 130K | 4.19M | 0 | 0 |
| 2024-03-31 | ALPHACENTRIC ADVISORS LLC | 0.16% | 105K | 3.38M | 0 | 0 |
| 2024-03-31 | AMERIPRISE FINANCIAL INC | 0.16% | 104.22K | 3.36M | -2.62K | -2.46% |
| 2024-03-31 | GOLDMAN SACHS GROUP INC | 0.14% | 91.49K | 2.95M | -27.6K | -23.18% |
| 2024-03-31 | 683 CAPITAL MANAGEMENT, LLC | 0.09% | 58K | 1.87M | 0 | 0 |
| 2024-03-31 | CITIGROUP INC | 0.05% | 30K | 966K | 0 | 0 |
| 2024-03-31 | POINT72 ASSET MANAGEMENT, L.P. | 0.08% | 53.7K | 1.73M | -100.95K | -65.28% |
| 2024-03-31 | D. E. SHAW & CO., INC. | 0.08% | 51.67K | 1.66M | -23.97K | -31.69% |
| 2024-03-31 | SUVRETTA CAPITAL MANAGEMENT, LLC | 0.07% | 47.2K | 1.52M | 0 | 0 |
| 2024-03-31 | ALPS ADVISORS INC | 0.07% | 46.71K | 1.5M | 990 | +2.17% |
| 2024-03-31 | DIMENSIONAL FUND ADVISORS LP | 0.06% | 38.18K | 1.23M | -249 | -0.65% |
| 2024-03-31 | GEODE CAPITAL MANAGEMENT, LLC | 0.02% | 12.09K | 389.3K | 1.1K | +9.96% |
| 2024-03-31 | BARCLAYS PLC | 0.02% | 11.8K | 380K | -100 | -0.84% |
| 2024-03-31 | DRIEHAUS CAPITAL MANAGEMENT LLC | 0.02% | 11.24K | 361.77K | 0 | 0 |
| 2024-03-31 | LMR PARTNERS LLP | 0.02% | 10.77K | 346.73K | 0 | 0 |
| 2024-03-31 | CITADEL ADVISORS LLC | 0.01% | 6.8K | 218.96K | -1.6K | -19.05% |
| 2024-03-31 | BAROMETER CAPITAL MANAGEMENT INC. | 0.01% | 7.72K | 219.55K | 4.72K | +157.23% |
| 2024-03-31 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0.01% | 7.11K | 228.81K | -49.05K | -87.35% |
| 2024-03-31 | AQUATIC CAPITAL MANAGEMENT LLC | 0.01% | 6.9K | 222.18K | 1.2K | +21.05% |
| 2024-03-31 | BNP PARIBAS ARBITRAGE, SNC | 0.01% | 5.33K | 171.56K | 4.73K | +783.58% |
| 2024-03-31 | JPMORGAN CHASE & CO | 0.01% | 4.4K | 141.71K | 4.4K | +73,250.00% |
| 2024-03-31 | CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. | 0.01% | 3.77K | 121K | 1.5K | +66.40% |
| 2024-03-31 | RHUMBLINE ADVISERS | 0.01% | 3.76K | 121.2K | 728 | +23.98% |
| 2024-03-31 | GROUP ONE TRADING, L.P. | 0% | 3K | 96.5K | -16.97K | -84.99% |
| 2024-03-31 | SIGNATUREFD, LLC | 0% | 2.61K | 84.17K | 644 | +32.69% |
| 2024-03-31 | OPTIVER HOLDING B.V. | 0% | 2.04K | 65.56K | -47.92K | -95.92% |
| 2024-03-31 | UBS GROUP AG | 0% | 1.38K | 44.34K | -582 | -29.71% |
| 2024-03-31 | VAN ECK ASSOCIATES CORP | 0% | 1.21K | 39K | 62 | +5.41% |
| 2024-03-31 | CACTI ASSET MANAGEMENT LLC | 0% | 1K | 32.95K | 0 | 0 |
| 2024-03-31 | HEADLANDS TECHNOLOGIES LLC | 0% | 787 | 25.34K | 712 | +949.33% |
| 2024-03-31 | GAMMA INVESTING LLC | 0% | 775 | 24.96K | -386 | -33.25% |
| 2024-03-31 | NEW YORK STATE COMMON RETIREMENT FUND | 0% | 554 | 18K | -40 | -6.73% |
| 2024-03-31 | WELLS FARGO & COMPANY/MN | 0% | 432 | 13.91K | 432 | +100.00% |
| 2024-03-31 | RISE ADVISORS, LLC | 0% | 425 | 13.69K | 425 | +100.00% |
| 2024-03-31 | SIMPLEX TRADING, LLC | 0% | 385 | 12K | 385 | +100.00% |
| 2024-03-31 | US BANCORP \DE\ | 0% | 359 | 11.56K | -462 | -56.27% |
| 2024-03-31 | LINDBROOK CAPITAL, LLC | 0% | 221 | 7.12K | -8 | -3.49% |
| 2024-03-31 | LAZARD ASSET MANAGEMENT LLC | 0% | 122 | 3K | -51 | -29.48% |
| 2024-03-31 | PARALLEL ADVISORS, LLC | 0% | 89 | 2.87K | -311 | -77.75% |
| 2024-03-31 | ADVISOR GROUP HOLDINGS, INC. | 0% | 81 | 2.61K | 43 | +113.16% |
| 2024-03-31 | RFP FINANCIAL GROUP LLC | 0% | 68 | 2.19K | 68 | +100.00% |
| 2024-03-31 | PNC FINANCIAL SERVICES GROUP, INC. | 0% | 63 | 2.03K | 63 | +100.00% |
| 2023-12-31 | ALPHACENTRIC ADVISORS LLC | 0.16% | 105K | 4.27M | 0 | 0 |
| 2023-12-31 | D. E. SHAW & CO., INC. | 0.11% | 75.64K | 3.07M | 18.3K | +31.90% |
| 2023-12-31 | MILLENNIUM MANAGEMENT LLC | 0.09% | 62.56K | 2.54M | 40.18K | +179.53% |
| 2023-12-31 | 683 CAPITAL MANAGEMENT, LLC | 0.09% | 58K | 2.36M | 0 | 0 |
| 2023-12-31 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0.08% | 56.16K | 2.28M | 48.7K | +653.21% |
| 2023-12-31 | OPTIVER HOLDING B.V. | 0.08% | 49.96K | 2.03M | 49.96K | +100.00% |
| 2023-12-31 | SUVRETTA CAPITAL MANAGEMENT, LLC | 0.07% | 47.2K | 1.92M | 0 | 0 |
| 2023-12-31 | ALPS ADVISORS INC | 0.07% | 45.72K | 1.86M | -2.59K | -5.36% |
| 2023-12-31 | CUBIST SYSTEMATIC STRATEGIES, LLC | 0.07% | 45.41K | 1.85M | 22.16K | +95.31% |
| 2023-12-31 | JANE STREET GROUP, LLC | 0.06% | 42.68K | 1.74M | 42.68K | +100.00% |
| 2023-12-31 | DIMENSIONAL FUND ADVISORS LP | 0.06% | 38.43K | 1.56M | 31.33K | +440.76% |
| 2023-12-31 | OLD MISSION CAPITAL LLC | 0.05% | 33.98K | 1.38M | 33.98K | +100.00% |
| 2023-12-31 | AMERICAN CENTURY COMPANIES INC | 0.04% | 23.47K | 954.1K | 1.34K | +6.07% |
| 2023-12-31 | MOODY NATIONAL BANK TRUST DIVISION | 0.03% | 22.52K | 915.36K | 3.68K | +19.53% |
| 2023-12-31 | BANK OF AMERICA CORP /DE/ | 0.03% | 20.81K | 846.01K | 1.37K | +7.02% |
| 2023-12-31 | GROUP ONE TRADING, L.P. | 0.03% | 19.97K | 811.78M | 19.87K | +20,702.08% |
| 2023-12-31 | HIGHVISTA STRATEGIES LLC | 0.02% | 12.95K | 526.54K | -694 | -5.09% |
| 2023-12-31 | ACADIAN ASSET MANAGEMENT LLC | 0.02% | 12.82K | 520K | -6.33K | -33.05% |
| 2023-12-31 | BARCLAYS PLC | 0.02% | 11.9K | 484K | -11.9K | -50.00% |
| 2023-12-31 | BANK OF MONTREAL /CAN/ | 0.02% | 11.57K | 473.86K | 4.25K | +58.09% |
| 2023-12-31 | DRIEHAUS CAPITAL MANAGEMENT LLC | 0.02% | 11.24K | 456.7K | 0 | 0 |
| 2023-12-31 | GEODE CAPITAL MANAGEMENT, LLC | 0.02% | 11K | 446.95K | 900 | +8.92% |
| 2023-12-31 | LMR PARTNERS LLP | 0.02% | 10.77K | 437.72K | 0 | 0 |
| 2023-12-31 | TWO SIGMA INVESTMENTS, LP | 0.02% | 10.13K | 411.62K | -2.07K | -17.00% |
| 2023-12-31 | WALLEYE CAPITAL LLC | 0.01% | 9K | 365.77K | 9K | +100.00% |
| 2023-12-31 | ECOR1 CAPITAL, LLC | 8.69% | 5.76M | 233.99M | 0 | 0 |
| 2023-12-31 | FMR LLC | 6.39% | 4.23M | 172.1M | -83.87K | -1.94% |
| 2023-12-31 | BVF INC/IL | 2.89% | 1.92M | 77.85M | 0 | 0 |
| 2023-12-31 | SEGALL BRYANT & HAMILL, LLC | 1.32% | 874.73K | 35.56M | 136.74K | +18.53% |
| 2023-12-31 | PROSIGHT MANAGEMENT, LP | 1.25% | 827.29K | 33.63M | 97.09K | +13.30% |
| 2023-12-31 | PRIMECAP MANAGEMENT CO/CA/ | 1.02% | 678.88K | 27.6M | 9.2K | +1.37% |
| 2023-12-31 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 0.94% | 622.11K | 25.29M | 622.11K | +100.00% |
| 2023-12-31 | WELLINGTON MANAGEMENT GROUP LLP | 0.75% | 495.22K | 20.13M | 495.22K | +100.00% |
| 2023-12-31 | BLACKROCK INC. | 0.7% | 463.26K | 18.83M | 22.66K | +5.14% |
| 2023-12-31 | FINEPOINT CAPITAL LP | 0.69% | 458.66K | 18.64M | 0 | 0 |
| 2023-12-31 | HUDSON BAY CAPITAL MANAGEMENT LP | 0.5% | 332K | 13.5M | -18K | -5.14% |
| 2023-12-31 | RENAISSANCE TECHNOLOGIES LLC | 0.4% | 263.2K | 10.7M | -18.6K | -6.60% |
| 2023-12-31 | CITADEL ADVISORS LLC | 0.4% | 262.38K | 10.67M | -207.48K | -44.16% |
| 2023-12-31 | STONEPINE CAPITAL MANAGEMENT, LLC | 0.4% | 261.87K | 10.65M | -540.67K | -67.37% |
| 2023-12-31 | NEWTYN MANAGEMENT, LLC | 0.33% | 218.09K | 8.87M | -56.91K | -20.70% |
| 2023-12-31 | GREENLIGHT CAPITAL INC | 0.25% | 162.58K | 6.61M | 6.2K | +3.96% |
| 2023-12-31 | POINT72 ASSET MANAGEMENT, L.P. | 0.23% | 154.65K | 6.29M | -18.65K | -10.76% |
| 2023-12-31 | DAFNA CAPITAL MANAGEMENT LLC | 0.2% | 130.18K | 5.29M | 70K | +116.33% |
| 2023-12-31 | | 0.2% | 130K | 5.28M | 130K | +100.00% |
| 2023-12-31 | NORGES BANK | 0.18% | 120K | 4.88M | 120K | +100.00% |
| 2023-12-31 | GOLDMAN SACHS GROUP INC | 0.18% | 119.09K | 4.84M | 43.92K | +58.43% |
| 2023-12-31 | MORGAN STANLEY | 0.17% | 111.33K | 4.53M | 87.98K | +376.79% |
| 2023-12-31 | AMERIPRISE FINANCIAL INC | 0.16% | 106.84K | 4.34M | 17.5K | +19.59% |
| 2023-12-31 | CITIGROUP INC | 0.05% | 30K | 1.22M | 30K | +100.00% |
