Ionis Pharmaceuticals (IONS) insider trading activity: Get Latest News Today

IONS Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.49

Short Percent Of Float7.57

Shares Outstanding157.90M

Shares Float156.63M

Shares Short10.24M

Short Ratio6.49

7.57%

Short % of Float

6.49%

Short % of Shares Outstanding

Market Insider IONS

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.83% Percentage of Shares held by All Insiders

105.05% Percentage of Shares held by All Institutions

105.93% Percentage of Float held by Institutions

507

Number of Institutions Holding Shares

Institutional Ownership

About 105.05% of IONS shares are held by financial institutions. LIONTRUST INVESTMENT PARTNERS LLP is the top corporate investor, holding 288.54K shares valued at $12.51M. A 0.2% stake in Ionis Pharmaceuticals, Inc. is owned by the company. VANGUARD GROUP INC owns 13.43M shares valued at $582.21M, which translates its holding of 9.38% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2024	LIONTRUST INVESTMENT PARTNERS LLP	0.2%	288.54K	12.51M	4.56K	+1.61%
Mar 31, 2024	VANGUARD GROUP INC	9.38%	13.43M	582.21M	-773.03K	-5.44%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	3.12%	4.47M	193.61M	-241.29K	-5.13%
Mar 31, 2024	STATE STREET CORP	2.9%	4.16M	180.15M	146.87K	+3.66%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	2.61%	3.74M	163.17M	221.44K	+6.29%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.46%	3.52M	152.69M	-732.87K	-17.22%
Mar 31, 2024	TWEEDY, BROWNE CO LLC	2.41%	3.45M	149.76M	0	0
Mar 31, 2024	MACQUARIE GROUP LTD	2.24%	3.2M	138.75M	112.34K	+3.64%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.65%	2.36M	102.51M	88.33K	+3.88%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.41%	2.01M	87.26M	-51.76K	-2.51%
Mar 31, 2024	ARK INVESTMENT MANAGEMENT LLC	0.98%	1.4M	60.68M	-505.2K	-26.52%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.96%	1.37M	59.54M	124.41K	+9.96%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.91%	1.3M	56.41M	26.05K	+2.04%
Mar 31, 2024	MORGAN STANLEY	0.81%	1.16M	50.44M	73.34K	+6.73%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.76%	1.08M	46.99M	282.43K	+35.24%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.73%	1.04M	45.09M	263.1K	+33.86%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.7%	1M	43.35M	-385.3K	-27.81%
Mar 31, 2024	JPMORGAN CHASE & CO	0.44%	630.98K	27.35M	-310.05K	-32.95%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.42%	606.3K	26.28M	151.22K	+33.23%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.41%	584.16K	25.32M	-10.09K	-1.70%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.41%	583.59K	25.3M	-57.47K	-8.97%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.41%	583.18K	25.28M	-307.15K	-34.50%
Mar 31, 2024	BARCLAYS PLC	0.4%	577.39K	25.03M	-67.12K	-10.41%
Mar 31, 2024	JACOBS LEVY EQUITY MANAGEMENT, INC	0.4%	571.76K	24.79M	62.23K	+12.21%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.3%	13.32M	577.3M	115.66K	+0.88%
Mar 31, 2024	BLACKROCK INC.	6.82%	9.77M	423.61M	714.36K	+7.89%
Mar 31, 2024	BELLEVUE GROUP AG	5.8%	8.3M	359.78M	-414.47K	-4.76%
Mar 31, 2024	CANDRIAM S.C.A.	0.64%	911.9K	39.53M	282.83K	+44.96%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.63%	898.36K	38.94M	-58.49K	-6.11%
Mar 31, 2024	NOMURA HOLDINGS INC	0.33%	470.84K	20.41M	-18.35K	-3.75%
Mar 31, 2024	AXA S.A.	0.32%	464.82K	20.15M	74	+0.02%
Mar 31, 2024	CAPITAL WORLD INVESTORS	0.59%	839.46K	36.39M	0	0
Mar 31, 2024	PINNACLE ASSOCIATES LTD	0.32%	459.76K	19.93M	779	+0.17%
Mar 31, 2024	INVESCO LTD.	0.31%	442.89K	19.2M	236.99K	+115.10%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.3%	423.03K	18.34M	99.02K	+30.56%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.29%	421.49K	18.27M	64.81K	+18.17%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.29%	416.73K	18.07M	416.73K	+100.00%
Mar 31, 2024	EVERSEPT PARTNERS, LP	0.26%	376.44K	16.32M	51.78K	+15.95%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.23%	335.5K	14.54M	190.5K	+131.38%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.21%	300K	13.01M	0	0
Mar 31, 2024	BAILLIE GIFFORD & CO	0.21%	295.68K	12.82M	-2.8K	-0.94%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	3.98%	5.7M	246.91M	1.08M	+23.36%
Mar 31, 2024	BVF INC/IL	1.7%	2.43M	105.28M	0	0
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.54%	778.59K	33.75M	438.93K	+129.22%
Mar 31, 2024	SQUAREPOINT OPS LLC	0.52%	745.17K	32.3M	685.97K	+1,158.65%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	0.51%	734K	31.82M	-821.02K	-52.80%
Mar 31, 2024	ROYAL BANK OF CANADA	0.51%	732.24K	31.74M	-42.01K	-5.43%
Mar 31, 2024	NORTHERN TRUST CORP	0.48%	692.25K	30.01M	4.26K	+0.62%
Mar 31, 2024	CUTTER CAPITAL MANAGEMENT, LP	0.2%	289.37K	12.54M	289.37K	+100.00%
Mar 31, 2024	FMR LLC	15.27%	21.86M	947.75M	341.86K	+1.59%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.2%	285.95K	12.4M	143.09K	+100.17%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.19%	271.26K	11.76M	86.86K	+47.10%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.19%	267.29K	11.59M	-21	-0.01%
Mar 31, 2024	GROUPAMA ASSET MANAGMENT	0.18%	257.87K	17.03M	-99.17K	-27.78%
Mar 31, 2024	SWISS NATIONAL BANK	0.18%	254.9K	11.05M	600	+0.24%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.17%	245.07K	10.62M	-15.64K	-6.00%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.17%	242.46K	10.51M	-3.57K	-1.45%
Mar 31, 2024	PRIVIUM FUND MANAGEMENT B.V.	0.16%	226.99K	9.84M	9.5K	+4.37%
Mar 31, 2024	CITIGROUP INC	0.16%	222.94K	9.66M	122.7K	+122.40%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.16%	222.82K	10.53M	-571	-0.26%
Mar 31, 2024	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.15%	220.26K	9.55M	-32.2K	-12.75%
Mar 31, 2024	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.15%	220.26K	9.55M	-32.2K	-12.75%
Mar 31, 2024	ABRDN PLC	0.15%	219.42K	9.51M	83K	+60.84%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.15%	215.89K	9.36M	192.41K	+819.32%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.15%	208.47K	9.04M	24.07K	+13.06%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.14%	203.95K	8.84M	-5.49K	-2.62%
Mar 31, 2024	ALTRINSIC GLOBAL ADVISORS LLC	0.14%	194.86K	8.45M	-14.29K	-6.83%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.14%	194.36K	8.43M	-160.6K	-45.24%
Mar 31, 2024	SICART ASSOCIATES LLC	0.14%	193.99K	8.41M	-300	-0.15%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.13%	193.08K	8.37M	-9.22K	-4.56%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	191.4K	8.3M	191.4K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.13%	191.16K	8.29M	-66.17K	-25.71%
Mar 31, 2024	CREDIT SUISSE AG/	0.13%	182.51K	7.91M	-7.21K	-3.80%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.13%	179.71K	7.79M	67.3K	+59.87%
Dec 31, 2023	VANGUARD GROUP INC	9.93%	14.2M	718.55M	-298.54K	-2.06%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.23%	13.2M	667.86M	78.4K	+0.60%
Dec 31, 2023	BLACKROCK INC.	6.33%	9.06M	458.22M	-57.1K	-0.63%
Dec 31, 2023	BELLEVUE GROUP AG	6.09%	8.71M	440.84M	-519.71K	-5.63%
Dec 31, 2023	CLEARBRIDGE INVESTMENTS, LLC	3.29%	4.71M	238.15M	-133.22K	-2.75%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	3.23%	4.62M	233.57M	4.62M	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.98%	4.26M	215.27M	497.08K	+13.23%
Dec 31, 2023	STATE STREET CORP	2.8%	4.01M	202.81M	53.77K	+1.36%
Dec 31, 2023		0.25%	356.68K	18.04M	356.68K	+100.00%
Dec 31, 2023	TWEEDY, BROWNE CO LLC	2.42%	3.45M	174.77M	-55.5K	-1.58%
Dec 31, 2023	MACQUARIE GROUP LTD	2.16%	3.09M	156.23M	152.31K	+5.19%
Dec 31, 2023	BVF INC/IL	1.7%	2.43M	122.86M	-1.58M	-39.35%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.59%	2.28M	115.16M	81.2K	+3.70%
Dec 31, 2023	ORBIMED ADVISORS LLC	1.44%	2.06M	104.46M	-104.7K	-4.83%
Dec 31, 2023	ARK INVESTMENT MANAGEMENT LLC	1.33%	1.91M	96.38M	-461.31K	-19.49%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	1.09%	1.56M	78.67M	828.02K	+113.90%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.97%	1.39M	70.08M	318.3K	+29.83%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.89%	1.28M	64.52M	33.01K	+2.66%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	0.87%	1.25M	63.19M	-1.59M	-55.93%
Dec 31, 2023	NORGES BANK	0.82%	1.17M	59.29M	1.17M	+100.00%
Dec 31, 2023	FIRST TRUST ADVISORS LP	0.77%	1.1M	55.53M	-37.25K	-3.28%
Dec 31, 2023	MORGAN STANLEY	0.76%	1.09M	55.16M	56.86K	+5.50%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.68%	968.8K	49.01M	827.3K	+584.66%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.67%	956.85K	48.41M	58K	+6.45%
Dec 31, 2023	JPMORGAN CHASE & CO	0.66%	941.03K	47.61M	39.98K	+4.44%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.62%	890.33K	45.04M	453.2K	+103.68%
Dec 31, 2023	CAMBER CAPITAL MANAGEMENT LP	0.6%	865K	43.76M	-1.39M	-61.56%
Dec 31, 2023	CAPITAL WORLD INVESTORS	0.59%	839.46K	42.47M	0	0
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.56%	801.45K	40.55M	325.39K	+68.35%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.54%	777.01K	39.31M	172.7K	+28.58%
Dec 31, 2023	ROYAL BANK OF CANADA	0.54%	774.25K	39.17M	110.8K	+16.70%
Dec 31, 2023	NORTHERN TRUST CORP	0.48%	687.99K	34.81M	-2.74K	-0.40%
Dec 31, 2023	BARCLAYS PLC	0.45%	644.51K	32.61M	4.96K	+0.77%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.45%	641.06K	32.43M	13.9K	+2.22%
Dec 31, 2023	CANDRIAM S.C.A.	0.44%	629.07K	31.83M	80K	+14.57%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.42%	594.25K	30.06M	-23.68K	-3.83%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.36%	509.53K	25.78M	136.42K	+36.56%
Dec 31, 2023	NOMURA HOLDINGS INC	0.34%	489.19K	24.75M	29.88K	+6.51%
Dec 31, 2023	AXA S.A.	0.33%	464.74K	23.51M	-16.84K	-3.50%
Dec 31, 2023	PINNACLE ASSOCIATES LTD	0.32%	458.98K	23.22M	-4.06K	-0.88%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.32%	455.08K	23.02M	-80.97K	-15.10%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.27%	381.38K	19.29M	43.56K	+12.89%
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.25%	354.96K	17.96M	-55.72K	-13.57%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.24%	339.67K	17.18M	339.67K	+100.00%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.23%	324.65K	16.42M	72.21K	+28.60%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.23%	324.01K	16.39M	14.86K	+4.81%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.22%	313.27K	15.85M	251.73K	+408.99%
Dec 31, 2023	FMR LLC	15.05%	21.52M	1.09B	21.95K	+0.10%

IONS Insiders

Among the IONS insiders holding of 0.83% of the stake in company, MONIA BRETT P, Chief Executive Officer, holds the largest shares of 180.98K. BERTHELSEN SPENCER R, director, is the second largest IONS insider with ownership of 147.26K shares. HOUGEN ELIZABETH L, EVP, Finance & CFO, stands third with possession of 110.5K shares of that stake.

Insiders	Designation	Shares Held
MONIA BRETT P	Chief Executive Officer	180.98K
BERTHELSEN SPENCER R	director	147.26K
HOUGEN ELIZABETH L	EVP, Finance & CFO	110.5K
GEARY RICHARD S	EVP, Chief Development Officer	99.08K
BENNETT C FRANK	EVP, Chief Scientific Officer	93.15K
PARSHALL B LYNNE	director	82.59K
SCHNEIDER EUGENE	EVP, Chf Clinical Develop Ofcr	61.06K
O'NEIL PATRICK R.	EVP CLO & General Counsel	56.25K
BIRCHLER BRIAN	EVP, Corp and Development Ops	55.05K
SWAYZE ERIC	EVP Research	48.02K
CADORET-MANIER ONAIZA	EVP,Chf GL Pdt Str & Oper Ofc	35.79K
HAYDEN MICHAEL R	director	32.72K
LOSCALZO JOSEPH	director	32.25K
MUTO FREDERICK T	director	31.68K
DEVERS SHANNON L.	EVP, Chief Human Resources Ofc	15.94K
DIAZ ALLENE M.	director	15.72K
BAROLDI JOSEPH	EVP, Chief Business Officer	3.07K
CROOKE STANLEY T	Exec Chairman of the Board	2.02K
KLEIN JOSEPH III	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 11, 2025	MONIA BRETT P	SALE	32.32	140	4.52K	180.98K
Feb 20, 2025	O'NEIL PATRICK R.	SALE	32.35	1.21K	39.05K	56.25K
Feb 04, 2025	O'NEIL PATRICK R.	SALE	31.62	6.17K	194.94K	57.45K
Feb 04, 2025	MONIA BRETT P	SALE	31.65	38.84K	1.23M	180.68K
Jan 31, 2025	BENNETT C FRANK	SALE	32.46	1.33K	43.08K	93.15K
Jan 31, 2025	GEARY RICHARD S	SALE	32.40	1.41K	45.56K	99.08K
Jan 31, 2025	MONIA BRETT P	SALE	32.45	13.24K	429.66K	219.53K
Jan 31, 2025	HOUGEN ELIZABETH L	SALE	32.44	1.52K	49.4K	110.5K
Jan 31, 2025	O'NEIL PATRICK R.	SALE	32.49	1.41K	45.68K	63.62K
Jan 31, 2025	SCHNEIDER EUGENE	SALE	32.20	1.48K	47.78K	61.06K
Jan 31, 2025	SWAYZE ERIC	SALE	32.31	1.37K	44.16K	48.02K
Jan 16, 2025	GEARY RICHARD S	SALE	32.86	7.07K	232.41K	96.66K
Jan 16, 2025	MONIA BRETT P	SALE	32.63	33.45K	1.09M	207.4K
Jan 16, 2025	O'NEIL PATRICK R.	SALE	32.83	7.36K	241.63K	61.2K
Jan 16, 2025	SWAYZE ERIC	SALE	32.70	22	719.4	184
Jan 16, 2025	BENNETT C FRANK	SALE	32.90	6.75K	222.11K	90.87K
Jan 16, 2025	SCHNEIDER EUGENE	SALE	32.79	6.52K	213.89K	58.51K
Jan 16, 2025	HOUGEN ELIZABETH L	SALE	32.81	8.87K	290.99K	107.89K
Jan 16, 2025	BAROLDI JOSEPH	SALE	32.70	1.03K	33.65K	3.07K
Jan 16, 2025	BIRCHLER BRIAN	SALE	32.70	5.4K	176.58K	55.05K
Jan 16, 2025	DEVERS SHANNON L.	SALE	32.78	4.27K	139.86K	15.94K
Dec 23, 2024	HAYDEN MICHAEL R	PURCHASE	36.20	2.5K	90.5K	32.72K
Nov 12, 2024	LOSCALZO JOSEPH	SALE	37.86	13.51K	511.43K	32.25K
Nov 12, 2024	SWAYZE ERIC	SALE	37.92	1.19K	45.28K	33.71K
Nov 12, 2024	MONIA BRETT P	SALE	38.05	6.63K	252.29K	167.39K
Oct 16, 2024	SWAYZE ERIC	SALE	38.31	53	2.03K	157
Aug 29, 2024	GEARY RICHARD S	SALE	49.63	331	16.43K	84.82K
Aug 28, 2024	GEARY RICHARD S	SALE	49.16	320	15.73K	85.15K
Aug 05, 2024	GEARY RICHARD S	SALE	48.00	2.43K	116.64K	85.51K
Jul 16, 2024	KLEIN JOSEPH III	SALE	50.00	12K	600K	0
Jul 16, 2024	DIAZ ALLENE M.	SALE	50.17	737	36.98K	15.72K
Jun 17, 2024	BERTHELSEN SPENCER R	SALE	40.29	16K	644.64K	147.26K
May 03, 2024	KLEIN JOSEPH III	SALE	42.90	930	39.89K	0
Apr 16, 2024	BIRCHLER BRIAN	SALE	41.66	905	37.7K	46.16K
Apr 16, 2024	BAROLDI JOSEPH	SALE	41.60	4.01K	166.64K	19.63K
Feb 16, 2024	MONIA BRETT P	SALE	44.49	387	17.22K	173.75K
Feb 02, 2024	GEARY RICHARD S	SALE	50.04	2K	99.84K	87.3K
Feb 02, 2024	HOUGEN ELIZABETH L	SALE	49.54	2.16K	107.11K	92.87K
Feb 02, 2024	MONIA BRETT P	SALE	49.37	23.91K	1.18M	173.73K
Feb 02, 2024	CADORET-MANIER ONAIZA	SALE	49.60	2.16K	107.24K	35.79K
Feb 02, 2024	SWAYZE ERIC	SALE	49.56	1.94K	96.15K	34.29K
Feb 02, 2024	BENNETT C FRANK	SALE	49.52	1.89K	93.34K	79.05K
Feb 02, 2024	SCHNEIDER EUGENE	SALE	49.59	2.11K	104.44K	47.66K
Feb 02, 2024	O'NEIL PATRICK R.	SALE	49.67	2K	99.1K	48.63K
Jan 31, 2024	SWAYZE ERIC	SALE	52.00	10.77K	560.2K	32.52K
Jan 25, 2024	MONIA BRETT P	SALE	51.75	2.29K	118.25K	151.85K
Jan 25, 2024	O'NEIL PATRICK R.	SALE	51.75	6.45K	333.79K	46.8K
Jan 17, 2024	MONIA BRETT P	SALE	50.42	32.06K	1.62M	154.14K
Jan 17, 2024	GEARY RICHARD S	SALE	50.42	7.34K	369.96K	85.48K
Jan 17, 2024	BIRCHLER BRIAN	SALE	50.42	4.5K	226.73K	44.58K
Jan 17, 2024	SWAYZE ERIC	SALE	50.42	9	453.75	85
Jan 17, 2024	CADORET-MANIER ONAIZA	SALE	50.42	5.56K	280.52K	33.81K
Jan 17, 2024	HOUGEN ELIZABETH L	SALE	50.42	8.68K	437.77K	90.89K
Jan 17, 2024	BENNETT C FRANK	SALE	50.42	6.75K	340.06K	77.32K
Jan 17, 2024	BAROLDI JOSEPH	SALE	50.42	564	28.44K	1.64K
Jan 17, 2024	SCHNEIDER EUGENE	SALE	50.42	5.48K	276.39K	47.85K
Jan 17, 2024	O'NEIL PATRICK R.	SALE	50.42	7.74K	390.43K	53.25K
Jan 12, 2024	SCHNEIDER EUGENE	SALE	53.50	8K	428K	38.17K
Dec 28, 2023	PARSHALL B LYNNE	SALE	50.19	42.53K	2.13M	82.59K
Dec 28, 2023	SWAYZE ERIC	SALE	50.19	27.1K	1.36M	32.52K
Dec 27, 2023	PARSHALL B LYNNE	SALE	50.23	50K	2.51M	82.59K
Dec 26, 2023	PARSHALL B LYNNE	SALE	51.46	25.11K	1.29M	82.59K
Dec 26, 2023	O'NEIL PATRICK R.	SALE	51.46	20.83K	1.07M	40.36K
Dec 26, 2023	SCHNEIDER EUGENE	SALE	51.46	25K	1.29M	36.05K
Dec 21, 2023	MONIA BRETT P	SALE	49.29	17.5K	862.58K	118.11K
Dec 21, 2023	GEARY RICHARD S	SALE	49.29	4.11K	202.68K	72.96K
Dec 21, 2023	BENNETT C FRANK	SALE	49.29	16.11K	794.21K	65.75K
Dec 20, 2023	MONIA BRETT P	SALE	49.64	6.5K	322.64K	118.11K
Dec 20, 2023	GEARY RICHARD S	SALE	49.64	6.5K	322.64K	72.96K
Dec 20, 2023	BENNETT C FRANK	SALE	49.64	6.5K	322.64K	65.75K
Dec 14, 2023	MONIA BRETT P	SALE	50.19	9.14K	458.71K	118.11K
Dec 14, 2023	BENNETT C FRANK	SALE	50.19	8.61K	432.11K	65.75K
Dec 14, 2023	GEARY RICHARD S	SALE	50.19	4.04K	202.86K	72.96K
Nov 15, 2023	KLEIN JOSEPH III	SALE	50.00	2K	100K	16.35K
Oct 17, 2023	SWAYZE ERIC	SALE	47.95	52	2.49K	73
Oct 12, 2023	MONIA BRETT P	SALE	46.00	3.77K	173.42K	118.11K
Sep 28, 2023	BENNETT C FRANK	SALE	46.50	4.46K	207.39K	65.75K
Sep 26, 2023	KLEIN JOSEPH III	SALE	45.13	2K	90.25K	18.35K
Sep 26, 2023	PARSHALL B LYNNE	SALE	45.13	10K	451.27K	82.59K
Aug 01, 2023	DIAZ ALLENE M.	SALE	41.05	657	26.97K	12.68K
Jul 18, 2023	KLEIN JOSEPH III	SALE	42.00	3.56K	149.31K	20.35K
Jul 07, 2023	MONIA BRETT P	SALE	42.25	18.65K	787.95K	121.72K
May 24, 2023	O'NEIL PATRICK R.	SALE	41.70	1.53K	63.68K	40.36K
May 22, 2023	MONIA BRETT P	SALE	40.14	2.63K	105.57K	140.37K
Apr 18, 2023	BIRCHLER BRIAN	SALE	36.50	672	24.53K	36.53K
Apr 18, 2023	BAROLDI JOSEPH	SALE	36.50	3.88K	141.63K	10.57K
Apr 18, 2023	CADORET-MANIER ONAIZA	SALE	36.50	2.58K	94.25K	24.31K
Feb 06, 2023	HOUGEN ELIZABETH L	SALE	40.59	2.08K	84.39K	75.5K
Feb 06, 2023	SWAYZE ERIC	SALE	40.79	1.82K	74.03K	31.94K
Feb 06, 2023	MONIA BRETT P	SALE	40.69	24.65K	1M	145.31K
Feb 06, 2023	O'NEIL PATRICK R.	SALE	40.86	1.92K	78.46K	41.58K
Feb 06, 2023	GEARY RICHARD S	SALE	40.66	1.92K	78.07K	72.39K
Feb 06, 2023	BENNETT C FRANK	SALE	40.57	1.81K	73.56K	69.65K
Feb 06, 2023	CADORET-MANIER ONAIZA	SALE	40.66	1.45K	59K	21.23K
Feb 06, 2023	SCHNEIDER EUGENE	SALE	40.67	1.41K	57.46K	24.95K
Jan 31, 2023	O'NEIL PATRICK R.	SALE	39.71	4.5K	178.7K	39.68K
Jan 30, 2023	O'NEIL PATRICK R.	SALE	39.42	4.5K	177.37K	44.18K
Jan 18, 2023	SCHNEIDER EUGENE	SALE	39.57	4.75K	188.05K	22.33K
Jan 18, 2023	BAROLDI JOSEPH	SALE	39.79	375	14.92K	851
Jan 18, 2023	BENNETT C FRANK	SALE	38.89	6.98K	271.36K	67.86K
Jan 18, 2023	SWAYZE ERIC	SALE	39.74	5.63K	223.8K	30.04K
Jan 18, 2023	O'NEIL PATRICK R.	SALE	39.49	7.84K	309.48K	48.68K
Jan 18, 2023	CADORET-MANIER ONAIZA	SALE	39.55	3.75K	148.22K	18.54K
Jan 18, 2023	HOUGEN ELIZABETH L	SALE	39.70	8.28K	328.72K	73.44K
Jan 18, 2023	MONIA BRETT P	SALE	39.49	25.07K	989.95K	120.86K
Jan 18, 2023	GEARY RICHARD S	SALE	39.57	7.87K	311.53K	70.48K
Jan 17, 2023	KLEIN JOSEPH III	SALE	40.00	2K	80K	16.79K
Sep 08, 2022	SWAYZE ERIC	SALE	44.55	460	20.49K	19.89K
Aug 05, 2022	SWAYZE ERIC	SALE	45.20	1	45.2	20.35K
Jul 15, 2022	KLEIN JOSEPH III	SALE	38.78	644	24.97K	18.79K
Apr 21, 2022	SWAYZE ERIC	SALE	44.15	378	16.69K	20.35K
Apr 12, 2022	O'NEIL PATRICK R.	SALE	40.06	6.79K	272.06K	34.54K
Apr 01, 2022	MONIA BRETT P	SALE	37.49	355	13.31K	88.66K
Jul 15, 2021	KLEIN JOSEPH III	SALE	35.30	4.33K	152.99K	18.13K
Jun 23, 2021	BERTHELSEN SPENCER R	SALE	37.74	15K	566.1K	100.98K
Jun 15, 2021	MUTO FREDERICK T	SALE	36.50	5K	182.5K	31.68K
Mar 01, 2021	MONIA BRETT P	SALE	54.27	236	12.81K	50.11K
Jan 26, 2021	CROOKE STANLEY T	SALE	63.74	28.33K	1.81M	2.02K
Jan 25, 2021	O'NEIL PATRICK R.	SALE	63.50	5.32K	338.07K	26.5K
Jan 22, 2021	CROOKE STANLEY T	SALE	61.67	40K	2.47M	494.39K
Jan 21, 2021	CROOKE STANLEY T	SALE	60.53	13.96K	844.88K	555.43K
Jan 13, 2021	GEARY RICHARD S	SALE	59.50	141	8.39K	30.31K
Jan 05, 2021	SWAYZE ERIC	SALE	55.99	195	10.92K	5.11K
Dec 23, 2020	PARSHALL B LYNNE	SALE	60.00	10K	600K	57.46K
Dec 15, 2020	CROOKE STANLEY T	SALE	49.77	39K	1.94M	600.39K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE2.5K1

SALES170.24K25

NET SHARES-167.74K24

NO. OF SHARES HELD2.13M26

% NET SHARES-107.86%-7.69%

Frequently Asked Questions

IONS Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.49

Short Percent Of Float7.57

Shares Outstanding157.90M

Shares Float156.63M

Shares Short10.24M

Short Ratio6.49

7.57%

Short % of Float

6.49%

Short % of Shares Outstanding

Market Insider IONS

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.83% Percentage of Shares held by All Insiders

105.05% Percentage of Shares held by All Institutions

105.93% Percentage of Float held by Institutions

507

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2024	LIONTRUST INVESTMENT PARTNERS LLP	0.2%	288.54K	12.51M	4.56K	+1.61%
Mar 31, 2024	VANGUARD GROUP INC	9.38%	13.43M	582.21M	-773.03K	-5.44%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	3.12%	4.47M	193.61M	-241.29K	-5.13%
Mar 31, 2024	STATE STREET CORP	2.9%	4.16M	180.15M	146.87K	+3.66%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	2.61%	3.74M	163.17M	221.44K	+6.29%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.46%	3.52M	152.69M	-732.87K	-17.22%
Mar 31, 2024	TWEEDY, BROWNE CO LLC	2.41%	3.45M	149.76M	0	0
Mar 31, 2024	MACQUARIE GROUP LTD	2.24%	3.2M	138.75M	112.34K	+3.64%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.65%	2.36M	102.51M	88.33K	+3.88%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.41%	2.01M	87.26M	-51.76K	-2.51%
Mar 31, 2024	ARK INVESTMENT MANAGEMENT LLC	0.98%	1.4M	60.68M	-505.2K	-26.52%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.96%	1.37M	59.54M	124.41K	+9.96%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.91%	1.3M	56.41M	26.05K	+2.04%
Mar 31, 2024	MORGAN STANLEY	0.81%	1.16M	50.44M	73.34K	+6.73%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.76%	1.08M	46.99M	282.43K	+35.24%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.73%	1.04M	45.09M	263.1K	+33.86%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.7%	1M	43.35M	-385.3K	-27.81%
Mar 31, 2024	JPMORGAN CHASE & CO	0.44%	630.98K	27.35M	-310.05K	-32.95%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.42%	606.3K	26.28M	151.22K	+33.23%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.41%	584.16K	25.32M	-10.09K	-1.70%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.41%	583.59K	25.3M	-57.47K	-8.97%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.41%	583.18K	25.28M	-307.15K	-34.50%
Mar 31, 2024	BARCLAYS PLC	0.4%	577.39K	25.03M	-67.12K	-10.41%
Mar 31, 2024	JACOBS LEVY EQUITY MANAGEMENT, INC	0.4%	571.76K	24.79M	62.23K	+12.21%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.3%	13.32M	577.3M	115.66K	+0.88%
Mar 31, 2024	BLACKROCK INC.	6.82%	9.77M	423.61M	714.36K	+7.89%
Mar 31, 2024	BELLEVUE GROUP AG	5.8%	8.3M	359.78M	-414.47K	-4.76%
Mar 31, 2024	CANDRIAM S.C.A.	0.64%	911.9K	39.53M	282.83K	+44.96%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.63%	898.36K	38.94M	-58.49K	-6.11%
Mar 31, 2024	NOMURA HOLDINGS INC	0.33%	470.84K	20.41M	-18.35K	-3.75%
Mar 31, 2024	AXA S.A.	0.32%	464.82K	20.15M	74	+0.02%
Mar 31, 2024	CAPITAL WORLD INVESTORS	0.59%	839.46K	36.39M	0	0
Mar 31, 2024	PINNACLE ASSOCIATES LTD	0.32%	459.76K	19.93M	779	+0.17%
Mar 31, 2024	INVESCO LTD.	0.31%	442.89K	19.2M	236.99K	+115.10%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.3%	423.03K	18.34M	99.02K	+30.56%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.29%	421.49K	18.27M	64.81K	+18.17%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.29%	416.73K	18.07M	416.73K	+100.00%
Mar 31, 2024	EVERSEPT PARTNERS, LP	0.26%	376.44K	16.32M	51.78K	+15.95%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.23%	335.5K	14.54M	190.5K	+131.38%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.21%	300K	13.01M	0	0
Mar 31, 2024	BAILLIE GIFFORD & CO	0.21%	295.68K	12.82M	-2.8K	-0.94%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	3.98%	5.7M	246.91M	1.08M	+23.36%
Mar 31, 2024	BVF INC/IL	1.7%	2.43M	105.28M	0	0
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.54%	778.59K	33.75M	438.93K	+129.22%
Mar 31, 2024	SQUAREPOINT OPS LLC	0.52%	745.17K	32.3M	685.97K	+1,158.65%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	0.51%	734K	31.82M	-821.02K	-52.80%
Mar 31, 2024	ROYAL BANK OF CANADA	0.51%	732.24K	31.74M	-42.01K	-5.43%
Mar 31, 2024	NORTHERN TRUST CORP	0.48%	692.25K	30.01M	4.26K	+0.62%
Mar 31, 2024	CUTTER CAPITAL MANAGEMENT, LP	0.2%	289.37K	12.54M	289.37K	+100.00%
Mar 31, 2024	FMR LLC	15.27%	21.86M	947.75M	341.86K	+1.59%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.2%	285.95K	12.4M	143.09K	+100.17%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.19%	271.26K	11.76M	86.86K	+47.10%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.19%	267.29K	11.59M	-21	-0.01%
Mar 31, 2024	GROUPAMA ASSET MANAGMENT	0.18%	257.87K	17.03M	-99.17K	-27.78%
Mar 31, 2024	SWISS NATIONAL BANK	0.18%	254.9K	11.05M	600	+0.24%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.17%	245.07K	10.62M	-15.64K	-6.00%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.17%	242.46K	10.51M	-3.57K	-1.45%
Mar 31, 2024	PRIVIUM FUND MANAGEMENT B.V.	0.16%	226.99K	9.84M	9.5K	+4.37%
Mar 31, 2024	CITIGROUP INC	0.16%	222.94K	9.66M	122.7K	+122.40%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.16%	222.82K	10.53M	-571	-0.26%
Mar 31, 2024	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.15%	220.26K	9.55M	-32.2K	-12.75%
Mar 31, 2024	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.15%	220.26K	9.55M	-32.2K	-12.75%
Mar 31, 2024	ABRDN PLC	0.15%	219.42K	9.51M	83K	+60.84%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.15%	215.89K	9.36M	192.41K	+819.32%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.15%	208.47K	9.04M	24.07K	+13.06%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.14%	203.95K	8.84M	-5.49K	-2.62%
Mar 31, 2024	ALTRINSIC GLOBAL ADVISORS LLC	0.14%	194.86K	8.45M	-14.29K	-6.83%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.14%	194.36K	8.43M	-160.6K	-45.24%
Mar 31, 2024	SICART ASSOCIATES LLC	0.14%	193.99K	8.41M	-300	-0.15%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.13%	193.08K	8.37M	-9.22K	-4.56%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	191.4K	8.3M	191.4K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.13%	191.16K	8.29M	-66.17K	-25.71%
Mar 31, 2024	CREDIT SUISSE AG/	0.13%	182.51K	7.91M	-7.21K	-3.80%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.13%	179.71K	7.79M	67.3K	+59.87%
Dec 31, 2023	VANGUARD GROUP INC	9.93%	14.2M	718.55M	-298.54K	-2.06%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.23%	13.2M	667.86M	78.4K	+0.60%
Dec 31, 2023	BLACKROCK INC.	6.33%	9.06M	458.22M	-57.1K	-0.63%
Dec 31, 2023	BELLEVUE GROUP AG	6.09%	8.71M	440.84M	-519.71K	-5.63%
Dec 31, 2023	CLEARBRIDGE INVESTMENTS, LLC	3.29%	4.71M	238.15M	-133.22K	-2.75%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	3.23%	4.62M	233.57M	4.62M	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.98%	4.26M	215.27M	497.08K	+13.23%
Dec 31, 2023	STATE STREET CORP	2.8%	4.01M	202.81M	53.77K	+1.36%
Dec 31, 2023		0.25%	356.68K	18.04M	356.68K	+100.00%
Dec 31, 2023	TWEEDY, BROWNE CO LLC	2.42%	3.45M	174.77M	-55.5K	-1.58%
Dec 31, 2023	MACQUARIE GROUP LTD	2.16%	3.09M	156.23M	152.31K	+5.19%
Dec 31, 2023	BVF INC/IL	1.7%	2.43M	122.86M	-1.58M	-39.35%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.59%	2.28M	115.16M	81.2K	+3.70%
Dec 31, 2023	ORBIMED ADVISORS LLC	1.44%	2.06M	104.46M	-104.7K	-4.83%
Dec 31, 2023	ARK INVESTMENT MANAGEMENT LLC	1.33%	1.91M	96.38M	-461.31K	-19.49%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	1.09%	1.56M	78.67M	828.02K	+113.90%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.97%	1.39M	70.08M	318.3K	+29.83%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.89%	1.28M	64.52M	33.01K	+2.66%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	0.87%	1.25M	63.19M	-1.59M	-55.93%
Dec 31, 2023	NORGES BANK	0.82%	1.17M	59.29M	1.17M	+100.00%
Dec 31, 2023	FIRST TRUST ADVISORS LP	0.77%	1.1M	55.53M	-37.25K	-3.28%
Dec 31, 2023	MORGAN STANLEY	0.76%	1.09M	55.16M	56.86K	+5.50%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.68%	968.8K	49.01M	827.3K	+584.66%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.67%	956.85K	48.41M	58K	+6.45%
Dec 31, 2023	JPMORGAN CHASE & CO	0.66%	941.03K	47.61M	39.98K	+4.44%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.62%	890.33K	45.04M	453.2K	+103.68%
Dec 31, 2023	CAMBER CAPITAL MANAGEMENT LP	0.6%	865K	43.76M	-1.39M	-61.56%
Dec 31, 2023	CAPITAL WORLD INVESTORS	0.59%	839.46K	42.47M	0	0
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.56%	801.45K	40.55M	325.39K	+68.35%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.54%	777.01K	39.31M	172.7K	+28.58%
Dec 31, 2023	ROYAL BANK OF CANADA	0.54%	774.25K	39.17M	110.8K	+16.70%
Dec 31, 2023	NORTHERN TRUST CORP	0.48%	687.99K	34.81M	-2.74K	-0.40%
Dec 31, 2023	BARCLAYS PLC	0.45%	644.51K	32.61M	4.96K	+0.77%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.45%	641.06K	32.43M	13.9K	+2.22%
Dec 31, 2023	CANDRIAM S.C.A.	0.44%	629.07K	31.83M	80K	+14.57%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.42%	594.25K	30.06M	-23.68K	-3.83%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.36%	509.53K	25.78M	136.42K	+36.56%
Dec 31, 2023	NOMURA HOLDINGS INC	0.34%	489.19K	24.75M	29.88K	+6.51%
Dec 31, 2023	AXA S.A.	0.33%	464.74K	23.51M	-16.84K	-3.50%
Dec 31, 2023	PINNACLE ASSOCIATES LTD	0.32%	458.98K	23.22M	-4.06K	-0.88%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.32%	455.08K	23.02M	-80.97K	-15.10%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.27%	381.38K	19.29M	43.56K	+12.89%
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.25%	354.96K	17.96M	-55.72K	-13.57%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.24%	339.67K	17.18M	339.67K	+100.00%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.23%	324.65K	16.42M	72.21K	+28.60%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.23%	324.01K	16.39M	14.86K	+4.81%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.22%	313.27K	15.85M	251.73K	+408.99%
Dec 31, 2023	FMR LLC	15.05%	21.52M	1.09B	21.95K	+0.10%

IONS Insiders

Insiders	Designation	Shares Held
MONIA BRETT P	Chief Executive Officer	180.98K
BERTHELSEN SPENCER R	director	147.26K
HOUGEN ELIZABETH L	EVP, Finance & CFO	110.5K
GEARY RICHARD S	EVP, Chief Development Officer	99.08K
BENNETT C FRANK	EVP, Chief Scientific Officer	93.15K
PARSHALL B LYNNE	director	82.59K
SCHNEIDER EUGENE	EVP, Chf Clinical Develop Ofcr	61.06K
O'NEIL PATRICK R.	EVP CLO & General Counsel	56.25K
BIRCHLER BRIAN	EVP, Corp and Development Ops	55.05K
SWAYZE ERIC	EVP Research	48.02K
CADORET-MANIER ONAIZA	EVP,Chf GL Pdt Str & Oper Ofc	35.79K
HAYDEN MICHAEL R	director	32.72K
LOSCALZO JOSEPH	director	32.25K
MUTO FREDERICK T	director	31.68K
DEVERS SHANNON L.	EVP, Chief Human Resources Ofc	15.94K
DIAZ ALLENE M.	director	15.72K
BAROLDI JOSEPH	EVP, Chief Business Officer	3.07K
CROOKE STANLEY T	Exec Chairman of the Board	2.02K
KLEIN JOSEPH III	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 11, 2025	MONIA BRETT P	SALE	32.32	140	4.52K	180.98K
Feb 20, 2025	O'NEIL PATRICK R.	SALE	32.35	1.21K	39.05K	56.25K
Feb 04, 2025	O'NEIL PATRICK R.	SALE	31.62	6.17K	194.94K	57.45K
Feb 04, 2025	MONIA BRETT P	SALE	31.65	38.84K	1.23M	180.68K
Jan 31, 2025	BENNETT C FRANK	SALE	32.46	1.33K	43.08K	93.15K
Jan 31, 2025	GEARY RICHARD S	SALE	32.40	1.41K	45.56K	99.08K
Jan 31, 2025	MONIA BRETT P	SALE	32.45	13.24K	429.66K	219.53K
Jan 31, 2025	HOUGEN ELIZABETH L	SALE	32.44	1.52K	49.4K	110.5K
Jan 31, 2025	O'NEIL PATRICK R.	SALE	32.49	1.41K	45.68K	63.62K
Jan 31, 2025	SCHNEIDER EUGENE	SALE	32.20	1.48K	47.78K	61.06K
Jan 31, 2025	SWAYZE ERIC	SALE	32.31	1.37K	44.16K	48.02K
Jan 16, 2025	GEARY RICHARD S	SALE	32.86	7.07K	232.41K	96.66K
Jan 16, 2025	MONIA BRETT P	SALE	32.63	33.45K	1.09M	207.4K
Jan 16, 2025	O'NEIL PATRICK R.	SALE	32.83	7.36K	241.63K	61.2K
Jan 16, 2025	SWAYZE ERIC	SALE	32.70	22	719.4	184
Jan 16, 2025	BENNETT C FRANK	SALE	32.90	6.75K	222.11K	90.87K
Jan 16, 2025	SCHNEIDER EUGENE	SALE	32.79	6.52K	213.89K	58.51K
Jan 16, 2025	HOUGEN ELIZABETH L	SALE	32.81	8.87K	290.99K	107.89K
Jan 16, 2025	BAROLDI JOSEPH	SALE	32.70	1.03K	33.65K	3.07K
Jan 16, 2025	BIRCHLER BRIAN	SALE	32.70	5.4K	176.58K	55.05K
Jan 16, 2025	DEVERS SHANNON L.	SALE	32.78	4.27K	139.86K	15.94K
Dec 23, 2024	HAYDEN MICHAEL R	PURCHASE	36.20	2.5K	90.5K	32.72K
Nov 12, 2024	LOSCALZO JOSEPH	SALE	37.86	13.51K	511.43K	32.25K
Nov 12, 2024	SWAYZE ERIC	SALE	37.92	1.19K	45.28K	33.71K
Nov 12, 2024	MONIA BRETT P	SALE	38.05	6.63K	252.29K	167.39K
Oct 16, 2024	SWAYZE ERIC	SALE	38.31	53	2.03K	157
Aug 29, 2024	GEARY RICHARD S	SALE	49.63	331	16.43K	84.82K
Aug 28, 2024	GEARY RICHARD S	SALE	49.16	320	15.73K	85.15K
Aug 05, 2024	GEARY RICHARD S	SALE	48.00	2.43K	116.64K	85.51K
Jul 16, 2024	KLEIN JOSEPH III	SALE	50.00	12K	600K	0
Jul 16, 2024	DIAZ ALLENE M.	SALE	50.17	737	36.98K	15.72K
Jun 17, 2024	BERTHELSEN SPENCER R	SALE	40.29	16K	644.64K	147.26K
May 03, 2024	KLEIN JOSEPH III	SALE	42.90	930	39.89K	0
Apr 16, 2024	BIRCHLER BRIAN	SALE	41.66	905	37.7K	46.16K
Apr 16, 2024	BAROLDI JOSEPH	SALE	41.60	4.01K	166.64K	19.63K
Feb 16, 2024	MONIA BRETT P	SALE	44.49	387	17.22K	173.75K
Feb 02, 2024	GEARY RICHARD S	SALE	50.04	2K	99.84K	87.3K
Feb 02, 2024	HOUGEN ELIZABETH L	SALE	49.54	2.16K	107.11K	92.87K
Feb 02, 2024	MONIA BRETT P	SALE	49.37	23.91K	1.18M	173.73K
Feb 02, 2024	CADORET-MANIER ONAIZA	SALE	49.60	2.16K	107.24K	35.79K
Feb 02, 2024	SWAYZE ERIC	SALE	49.56	1.94K	96.15K	34.29K
Feb 02, 2024	BENNETT C FRANK	SALE	49.52	1.89K	93.34K	79.05K
Feb 02, 2024	SCHNEIDER EUGENE	SALE	49.59	2.11K	104.44K	47.66K
Feb 02, 2024	O'NEIL PATRICK R.	SALE	49.67	2K	99.1K	48.63K
Jan 31, 2024	SWAYZE ERIC	SALE	52.00	10.77K	560.2K	32.52K
Jan 25, 2024	MONIA BRETT P	SALE	51.75	2.29K	118.25K	151.85K
Jan 25, 2024	O'NEIL PATRICK R.	SALE	51.75	6.45K	333.79K	46.8K
Jan 17, 2024	MONIA BRETT P	SALE	50.42	32.06K	1.62M	154.14K
Jan 17, 2024	GEARY RICHARD S	SALE	50.42	7.34K	369.96K	85.48K
Jan 17, 2024	BIRCHLER BRIAN	SALE	50.42	4.5K	226.73K	44.58K
Jan 17, 2024	SWAYZE ERIC	SALE	50.42	9	453.75	85
Jan 17, 2024	CADORET-MANIER ONAIZA	SALE	50.42	5.56K	280.52K	33.81K
Jan 17, 2024	HOUGEN ELIZABETH L	SALE	50.42	8.68K	437.77K	90.89K
Jan 17, 2024	BENNETT C FRANK	SALE	50.42	6.75K	340.06K	77.32K
Jan 17, 2024	BAROLDI JOSEPH	SALE	50.42	564	28.44K	1.64K
Jan 17, 2024	SCHNEIDER EUGENE	SALE	50.42	5.48K	276.39K	47.85K
Jan 17, 2024	O'NEIL PATRICK R.	SALE	50.42	7.74K	390.43K	53.25K
Jan 12, 2024	SCHNEIDER EUGENE	SALE	53.50	8K	428K	38.17K
Dec 28, 2023	PARSHALL B LYNNE	SALE	50.19	42.53K	2.13M	82.59K
Dec 28, 2023	SWAYZE ERIC	SALE	50.19	27.1K	1.36M	32.52K
Dec 27, 2023	PARSHALL B LYNNE	SALE	50.23	50K	2.51M	82.59K
Dec 26, 2023	PARSHALL B LYNNE	SALE	51.46	25.11K	1.29M	82.59K
Dec 26, 2023	O'NEIL PATRICK R.	SALE	51.46	20.83K	1.07M	40.36K
Dec 26, 2023	SCHNEIDER EUGENE	SALE	51.46	25K	1.29M	36.05K
Dec 21, 2023	MONIA BRETT P	SALE	49.29	17.5K	862.58K	118.11K
Dec 21, 2023	GEARY RICHARD S	SALE	49.29	4.11K	202.68K	72.96K
Dec 21, 2023	BENNETT C FRANK	SALE	49.29	16.11K	794.21K	65.75K
Dec 20, 2023	MONIA BRETT P	SALE	49.64	6.5K	322.64K	118.11K
Dec 20, 2023	GEARY RICHARD S	SALE	49.64	6.5K	322.64K	72.96K
Dec 20, 2023	BENNETT C FRANK	SALE	49.64	6.5K	322.64K	65.75K
Dec 14, 2023	MONIA BRETT P	SALE	50.19	9.14K	458.71K	118.11K
Dec 14, 2023	BENNETT C FRANK	SALE	50.19	8.61K	432.11K	65.75K
Dec 14, 2023	GEARY RICHARD S	SALE	50.19	4.04K	202.86K	72.96K
Nov 15, 2023	KLEIN JOSEPH III	SALE	50.00	2K	100K	16.35K
Oct 17, 2023	SWAYZE ERIC	SALE	47.95	52	2.49K	73
Oct 12, 2023	MONIA BRETT P	SALE	46.00	3.77K	173.42K	118.11K
Sep 28, 2023	BENNETT C FRANK	SALE	46.50	4.46K	207.39K	65.75K
Sep 26, 2023	KLEIN JOSEPH III	SALE	45.13	2K	90.25K	18.35K
Sep 26, 2023	PARSHALL B LYNNE	SALE	45.13	10K	451.27K	82.59K
Aug 01, 2023	DIAZ ALLENE M.	SALE	41.05	657	26.97K	12.68K
Jul 18, 2023	KLEIN JOSEPH III	SALE	42.00	3.56K	149.31K	20.35K
Jul 07, 2023	MONIA BRETT P	SALE	42.25	18.65K	787.95K	121.72K
May 24, 2023	O'NEIL PATRICK R.	SALE	41.70	1.53K	63.68K	40.36K
May 22, 2023	MONIA BRETT P	SALE	40.14	2.63K	105.57K	140.37K
Apr 18, 2023	BIRCHLER BRIAN	SALE	36.50	672	24.53K	36.53K
Apr 18, 2023	BAROLDI JOSEPH	SALE	36.50	3.88K	141.63K	10.57K
Apr 18, 2023	CADORET-MANIER ONAIZA	SALE	36.50	2.58K	94.25K	24.31K
Feb 06, 2023	HOUGEN ELIZABETH L	SALE	40.59	2.08K	84.39K	75.5K
Feb 06, 2023	SWAYZE ERIC	SALE	40.79	1.82K	74.03K	31.94K
Feb 06, 2023	MONIA BRETT P	SALE	40.69	24.65K	1M	145.31K
Feb 06, 2023	O'NEIL PATRICK R.	SALE	40.86	1.92K	78.46K	41.58K
Feb 06, 2023	GEARY RICHARD S	SALE	40.66	1.92K	78.07K	72.39K
Feb 06, 2023	BENNETT C FRANK	SALE	40.57	1.81K	73.56K	69.65K
Feb 06, 2023	CADORET-MANIER ONAIZA	SALE	40.66	1.45K	59K	21.23K
Feb 06, 2023	SCHNEIDER EUGENE	SALE	40.67	1.41K	57.46K	24.95K
Jan 31, 2023	O'NEIL PATRICK R.	SALE	39.71	4.5K	178.7K	39.68K
Jan 30, 2023	O'NEIL PATRICK R.	SALE	39.42	4.5K	177.37K	44.18K
Jan 18, 2023	SCHNEIDER EUGENE	SALE	39.57	4.75K	188.05K	22.33K
Jan 18, 2023	BAROLDI JOSEPH	SALE	39.79	375	14.92K	851
Jan 18, 2023	BENNETT C FRANK	SALE	38.89	6.98K	271.36K	67.86K
Jan 18, 2023	SWAYZE ERIC	SALE	39.74	5.63K	223.8K	30.04K
Jan 18, 2023	O'NEIL PATRICK R.	SALE	39.49	7.84K	309.48K	48.68K
Jan 18, 2023	CADORET-MANIER ONAIZA	SALE	39.55	3.75K	148.22K	18.54K
Jan 18, 2023	HOUGEN ELIZABETH L	SALE	39.70	8.28K	328.72K	73.44K
Jan 18, 2023	MONIA BRETT P	SALE	39.49	25.07K	989.95K	120.86K
Jan 18, 2023	GEARY RICHARD S	SALE	39.57	7.87K	311.53K	70.48K
Jan 17, 2023	KLEIN JOSEPH III	SALE	40.00	2K	80K	16.79K
Sep 08, 2022	SWAYZE ERIC	SALE	44.55	460	20.49K	19.89K
Aug 05, 2022	SWAYZE ERIC	SALE	45.20	1	45.2	20.35K
Jul 15, 2022	KLEIN JOSEPH III	SALE	38.78	644	24.97K	18.79K
Apr 21, 2022	SWAYZE ERIC	SALE	44.15	378	16.69K	20.35K
Apr 12, 2022	O'NEIL PATRICK R.	SALE	40.06	6.79K	272.06K	34.54K
Apr 01, 2022	MONIA BRETT P	SALE	37.49	355	13.31K	88.66K
Jul 15, 2021	KLEIN JOSEPH III	SALE	35.30	4.33K	152.99K	18.13K
Jun 23, 2021	BERTHELSEN SPENCER R	SALE	37.74	15K	566.1K	100.98K
Jun 15, 2021	MUTO FREDERICK T	SALE	36.50	5K	182.5K	31.68K
Mar 01, 2021	MONIA BRETT P	SALE	54.27	236	12.81K	50.11K
Jan 26, 2021	CROOKE STANLEY T	SALE	63.74	28.33K	1.81M	2.02K
Jan 25, 2021	O'NEIL PATRICK R.	SALE	63.50	5.32K	338.07K	26.5K
Jan 22, 2021	CROOKE STANLEY T	SALE	61.67	40K	2.47M	494.39K
Jan 21, 2021	CROOKE STANLEY T	SALE	60.53	13.96K	844.88K	555.43K
Jan 13, 2021	GEARY RICHARD S	SALE	59.50	141	8.39K	30.31K
Jan 05, 2021	SWAYZE ERIC	SALE	55.99	195	10.92K	5.11K
Dec 23, 2020	PARSHALL B LYNNE	SALE	60.00	10K	600K	57.46K
Dec 15, 2020	CROOKE STANLEY T	SALE	49.77	39K	1.94M	600.39K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE2.5K1

SALES170.24K25

NET SHARES-167.74K24

NO. OF SHARES HELD2.13M26

% NET SHARES-107.86%-7.69%

IONS Stock Ownership Breakdown

Ionis Pharmaceuticals, Inc.

IONS Stock Outstanding Shares

Market Insider IONS

Institutional Ownership

IONS Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

IONS Stock Outstanding Shares

Market Insider IONS

Institutional Ownership

IONS Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions