| Mar 31, 2024 | TD ASSET MANAGEMENT INC | 0.25% | 69.16K | 12.31B | 28.2K | +68.84% |
| Mar 31, 2024 | DECHENG CAPITAL LLC | 0.24% | 65.77K | 11.7M | 0 | 0 |
| Mar 31, 2024 | VERITION FUND MANAGEMENT LLC | 0.23% | 61.8K | 11M | -34.16K | -35.60% |
| Mar 31, 2024 | RAFFERTY ASSET MANAGEMENT, LLC | 0.2% | 53.37K | 9.5M | -30.65K | -36.48% |
| Mar 31, 2024 | CITIGROUP INC | 0.19% | 52.12K | 9.27M | 15.55K | +42.53% |
| Mar 31, 2024 | UBS GROUP AG | 0.19% | 51.03K | 9.08M | 20.27K | +65.89% |
| Mar 31, 2024 | SCOUT INVESTMENTS, INC. | 0.19% | 50.98K | 8.98M | 50.98K | +100.00% |
| Mar 31, 2024 | VESTAL POINT CAPITAL, LP | 0.17% | 45K | 8.01M | 45K | +100.00% |
| Mar 31, 2024 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0.15% | 41.3K | 7.35M | 12.05K | +41.19% |
| Mar 31, 2024 | SCHRODER INVESTMENT MANAGEMENT GROUP | 0.15% | 39.48K | 7.03M | -35.46K | -47.32% |
| Mar 31, 2024 | ABRDN PLC | 0.14% | 39.02K | 6.94M | 39.02K | +100.00% |
| Mar 31, 2024 | PRUDENTIAL FINANCIAL INC | 0.14% | 37.85K | 6.73M | -1.71K | -4.33% |
| Mar 31, 2024 | GW&K INVESTMENT MANAGEMENT, LLC | 0.14% | 37.53K | 6.68M | 37.53K | +100.00% |
| Mar 31, 2024 | SWISS NATIONAL BANK | 0.13% | 36.2K | 6.44M | 300 | +0.84% |
| Mar 31, 2024 | CI PRIVATE WEALTH, LLC | 0.13% | 35.97K | 6.4M | 35.97K | +100.00% |
| Mar 31, 2024 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 0.13% | 34.19K | 6.08M | -2.2K | -6.04% |
| Mar 31, 2024 | SEI INVESTMENTS CO | 0.12% | 33.75K | 6.01B | 18.97K | +128.30% |
| Mar 31, 2024 | HENNION & WALSH ASSET MANAGEMENT, INC. | 0.12% | 33.15K | 5.9M | 1.76K | +5.59% |
| Mar 31, 2024 | RHUMBLINE ADVISERS | 0.12% | 32.1K | 5.71M | 314 | +0.99% |
| Mar 31, 2024 | EAM GLOBAL INVESTORS LLC | 0.11% | 28.84K | 5.13M | 28.84K | +100.00% |
| Mar 31, 2024 | AFFINITY ASSET ADVISORS, LLC | 0.1% | 26.75K | 4.76M | 1.75K | +6.98% |
| Mar 31, 2024 | NUVEEN ASSET MANAGEMENT, LLC | 1.22% | 330.44K | 58.79M | 14.98K | +4.75% |
| Mar 31, 2024 | CREDIT SUISSE AG/ | 1.19% | 321.95K | 57.28M | -152.54K | -32.15% |
| Mar 31, 2024 | GOLDMAN SACHS GROUP INC | 1.6% | 434.57K | 77.32M | 206.52K | +90.56% |
| Mar 31, 2024 | WOODLINE PARTNERS LP | 1.01% | 275.46K | 49.01M | -206.52K | -42.85% |
| Mar 31, 2024 | MORGAN STANLEY | 0.81% | 218.83K | 38.94M | -100.89K | -31.56% |
| Mar 31, 2024 | SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) | 0.8% | 217.75K | 38.74M | -26.31K | -10.78% |
| Mar 31, 2024 | NORTHERN TRUST CORP | 0.76% | 205.08K | 36.49M | -4.12K | -1.97% |
| Mar 31, 2024 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.7% | 188.9K | 33.61M | 3.87K | +2.09% |
| Mar 31, 2024 | BRAIDWELL LP | 0.65% | 177.09K | 31.51M | -19.11K | -9.74% |
| Mar 31, 2024 | JPMORGAN CHASE & CO | 0.64% | 175.13K | 31.16M | -38.39K | -17.98% |
| Mar 31, 2024 | BAKER BROS. ADVISORS LP | 0.63% | 169.93K | 30.24M | 0 | 0 |
| Mar 31, 2024 | ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC | 0.58% | 158.43K | 28.19M | 99.1K | +167.05% |
| Mar 31, 2024 | PICTET ASSET MANAGEMENT HOLDING SA | 0.53% | 142.96K | 25.44M | -49.92K | -25.88% |
| Mar 31, 2024 | EVENTIDE ASSET MANAGEMENT, LLC | 0.5% | 136.49K | 24.28M | 0 | 0 |
| Mar 31, 2024 | C WORLDWIDE GROUP HOLDING A/S | 0.5% | 135.81K | 24.16M | -50K | -26.91% |
| Mar 31, 2024 | VICTORY CAPITAL MANAGEMENT INC | 0.5% | 134.82K | 23.99M | -38.06K | -22.01% |
| Mar 31, 2024 | FRANKLIN RESOURCES INC | 0.48% | 131.47K | 23.39M | 104.92K | +395.23% |
| Mar 31, 2024 | FIRST TURN MANAGEMENT, LLC | 0.48% | 130.85K | 23.28M | -111.34K | -45.97% |
| Mar 31, 2024 | BALYASNY ASSET MANAGEMENT L.P. | 0.46% | 124.2K | 22.1M | -132.4K | -51.60% |
| Mar 31, 2024 | DRIEHAUS CAPITAL MANAGEMENT LLC | 0.41% | 110.2K | 19.61M | -86.19K | -43.89% |
| Mar 31, 2024 | HANDELSBANKEN FONDER AB | 0.39% | 105.2K | 18.72M | -18K | -14.61% |
| Mar 31, 2024 | ROCK SPRINGS CAPITAL MANAGEMENT LP | 0.38% | 103.97K | 18.5M | 0 | 0 |
| Mar 31, 2024 | BOOTHBAY FUND MANAGEMENT, LLC | 0.38% | 102.8K | 18.29M | 3.6K | +3.63% |
| Mar 31, 2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.37% | 101.56K | 18.07M | 93.52K | +1,162.83% |
| Mar 31, 2024 | IKARIAN CAPITAL, LLC | 0.37% | 100K | 17.79M | 0 | 0 |
| Mar 31, 2024 | TIMESSQUARE CAPITAL MANAGEMENT, LLC | 0.36% | 97.16K | 17.29M | -153.31K | -61.21% |
| Mar 31, 2024 | CAPITAL WORLD INVESTORS | 0.36% | 97.15K | 17.29M | 97.15K | +100.00% |
| Mar 31, 2024 | MAN GROUP PLC | 0.35% | 95.86K | 17.06M | 45.02K | +88.56% |
| Mar 31, 2024 | JANE STREET GROUP, LLC | 0.35% | 93.75K | 16.68M | 43.13K | +85.20% |
| Mar 31, 2024 | S SQUARED TECHNOLOGY, LLC | 0.33% | 90.22K | 16.05M | -20K | -18.15% |
| Mar 31, 2024 | INVESCO LTD. | 0.33% | 89.63K | 15.95M | 35.4K | +65.28% |
| Mar 31, 2024 | SOLEUS CAPITAL MANAGEMENT, L.P. | 0.31% | 84.1K | 14.96M | 44.1K | +110.25% |
| Mar 31, 2024 | D. E. SHAW & CO., INC. | 0.3% | 82.03K | 14.6M | 14.89K | +22.17% |
| Mar 31, 2024 | BANK OF NEW YORK MELLON CORP | 0.33% | 89.84K | 15.99M | -8.81K | -8.93% |
| Mar 31, 2024 | FMR LLC | 15.63% | 4.24M | 755.12M | 1.86M | +77.87% |
| Mar 31, 2024 | AVORO CAPITAL ADVISORS LLC | 9.41% | 2.56M | 454.71M | -10K | -0.39% |
| Mar 31, 2024 | VANGUARD GROUP INC | 8.96% | 2.43M | 432.86M | -3K | -0.12% |
| Mar 31, 2024 | BLACKROCK INC. | 6.65% | 1.81M | 321.23M | -4.17K | -0.23% |
| Mar 31, 2024 | REDMILE GROUP, LLC | 5.55% | 1.51M | 268.36M | -224.94K | -12.98% |
| Mar 31, 2024 | FRAZIER LIFE SCIENCES MANAGEMENT, L.P. | 3.64% | 988.46K | 175.88M | 0 | 0 |
| Mar 31, 2024 | STATE STREET CORP | 3.48% | 944.55K | 168.06M | -292.95K | -23.67% |
| Mar 31, 2024 | JENNISON ASSOCIATES LLC | 2.47% | 670.74K | 119.34M | -53.61K | -7.40% |
| Mar 31, 2024 | PRICE T ROWE ASSOCIATES INC /MD/ | 2.43% | 658.62K | 117.19M | 231.26K | +54.11% |
| Mar 31, 2024 | DIMENSIONAL FUND ADVISORS LP | 2.11% | 572.92K | 101.94M | 22.11K | +4.01% |
| Mar 31, 2024 | GEODE CAPITAL MANAGEMENT, LLC | 1.94% | 525.75K | 93.56M | 14.5K | +2.84% |
| Mar 31, 2024 | HOOD RIVER CAPITAL MANAGEMENT LLC | 1.83% | 495.59K | 88.18M | 37.07K | +8.09% |
| Mar 31, 2024 | LORD, ABBETT & CO. LLC | 1.81% | 492.23K | 87.58M | -126.23K | -20.41% |
| Dec 31, 2023 | HOOD RIVER CAPITAL MANAGEMENT LLC | 1.64% | 458.51K | 56.88M | -1.98K | -0.43% |
| Dec 31, 2023 | PRICE T ROWE ASSOCIATES INC /MD/ | 1.52% | 427.36K | 53.02M | 171.16K | +66.80% |
| Dec 31, 2023 | IKARIAN CAPITAL, LLC | 0.36% | 100K | 12.41M | 100K | +100.00% |
| Dec 31, 2023 | MORGAN STANLEY | 1.14% | 319.72K | 39.66M | 31.17K | +10.80% |
| Dec 31, 2023 | NUVEEN ASSET MANAGEMENT, LLC | 1.13% | 315.47K | 39.14M | 53.23K | +20.30% |
| Dec 31, 2023 | BALYASNY ASSET MANAGEMENT L.P. | 0.92% | 256.6K | 31.83M | 223.96K | +686.12% |
| Dec 31, 2023 | TIMESSQUARE CAPITAL MANAGEMENT, LLC | 0.89% | 250.47K | 31.07M | 127.44K | +103.58% |
| Dec 31, 2023 | SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) | 0.87% | 244.06K | 30.28M | 0 | 0 |
| Dec 31, 2023 | | 0.23% | 65.77K | 8.16M | 65.77K | +100.00% |
| Dec 31, 2023 | GOLDMAN SACHS GROUP INC | 0.81% | 228.05K | 28.29M | 43.71K | +23.71% |
| Dec 31, 2023 | JPMORGAN CHASE & CO | 0.76% | 213.52K | 26.49M | -7.97K | -3.60% |
| Dec 31, 2023 | NORTHERN TRUST CORP | 0.75% | 209.2K | 25.95M | -4.06K | -1.91% |
| Dec 31, 2023 | DRIEHAUS CAPITAL MANAGEMENT LLC | 0.7% | 196.39K | 24.36M | -2.3K | -1.16% |
| Dec 31, 2023 | BRAIDWELL LP | 0.7% | 196.2K | 24.34M | 118.7K | +153.17% |
| Dec 31, 2023 | C WORLDWIDE GROUP HOLDING A/S | 0.66% | 185.81K | 23.05M | 0 | 0 |
| Dec 31, 2023 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.66% | 185.04K | 22.96M | 5.26K | +2.92% |
| Dec 31, 2023 | VICTORY CAPITAL MANAGEMENT INC | 0.62% | 172.88K | 21.45M | -36.61K | -17.48% |
| Dec 31, 2023 | BAKER BROS. ADVISORS LP | 0.61% | 169.93K | 21.08M | 0 | 0 |
| Dec 31, 2023 | FRED ALGER MANAGEMENT, LLC | 0.57% | 160.34K | 19.89M | -7.15K | -4.27% |
| Dec 31, 2023 | EVENTIDE ASSET MANAGEMENT, LLC | 0.49% | 136.49K | 16.93M | 136.49K | +100.00% |
| Dec 31, 2023 | HANDELSBANKEN FONDER AB | 0.44% | 123.2K | 15.28M | 10.4K | +9.22% |
| Dec 31, 2023 | S SQUARED TECHNOLOGY, LLC | 0.39% | 110.22K | 13.67M | 2K | +1.85% |
| Dec 31, 2023 | ROCK SPRINGS CAPITAL MANAGEMENT LP | 0.37% | 103.97K | 12.9M | 13.41K | +14.81% |
| Dec 31, 2023 | ORBIMED ADVISORS LLC | 0.37% | 103.7K | 12.87M | 103.7K | +100.00% |
| Dec 31, 2023 | BOOTHBAY FUND MANAGEMENT, LLC | 0.35% | 99.2K | 12.31M | 82.1K | +480.12% |
| Dec 31, 2023 | BANK OF NEW YORK MELLON CORP | 0.35% | 98.65K | 12.24M | 431 | +0.44% |
| Dec 31, 2023 | VERITION FUND MANAGEMENT LLC | 0.34% | 95.96K | 11.9M | -31.11K | -24.48% |
| Dec 31, 2023 | BANK OF AMERICA CORP /DE/ | 0.33% | 91.19K | 11.31M | 27.97K | +44.24% |
| Dec 31, 2023 | INTEGRAL HEALTH ASSET MANAGEMENT, LLC | 0.3% | 85K | 10.55M | 15K | +21.43% |
| Dec 31, 2023 | RAFFERTY ASSET MANAGEMENT, LLC | 0.3% | 84.02K | 10.42M | 12.22K | +17.01% |
| Dec 31, 2023 | EVERSEPT PARTNERS, LP | 0.29% | 80.8K | 10.02M | -27.97K | -25.72% |
| Dec 31, 2023 | SCHRODER INVESTMENT MANAGEMENT GROUP | 0.27% | 74.95K | 9.3M | 74.95K | +100.00% |
| Dec 31, 2023 | MARSHALL WACE, LLP | 0.25% | 70.9K | 8.8M | 61.37K | +644.13% |
| Dec 31, 2023 | D. E. SHAW & CO., INC. | 0.24% | 67.14K | 8.33M | 11.38K | +20.42% |
| Dec 31, 2023 | AVORO CAPITAL ADVISORS LLC | 9.15% | 2.57M | 318.28M | 0 | 0 |
| Dec 31, 2023 | VANGUARD GROUP INC | 8.69% | 2.44M | 302.18M | 35.63K | +1.48% |
| Dec 31, 2023 | FMR LLC | 8.51% | 2.39M | 295.99M | -243.49K | -9.26% |
| Dec 31, 2023 | BLACKROCK INC. | 6.45% | 1.81M | 224.49M | 107.3K | +6.30% |
| Dec 31, 2023 | REDMILE GROUP, LLC | 6.18% | 1.73M | 215.02M | -270.18K | -13.49% |
| Dec 31, 2023 | STATE STREET CORP | 4.41% | 1.24M | 153.52M | 205.67K | +19.93% |
| Dec 31, 2023 | FRAZIER LIFE SCIENCES MANAGEMENT, L.P. | 3.52% | 988.46K | 122.63M | 0 | 0 |
| Dec 31, 2023 | JENNISON ASSOCIATES LLC | 2.58% | 724.34K | 89.86M | 383.5K | +112.51% |
| Dec 31, 2023 | LORD, ABBETT & CO. LLC | 2.21% | 618.46K | 76.73M | -52.85K | -7.87% |
| Dec 31, 2023 | DIMENSIONAL FUND ADVISORS LP | 1.96% | 550.81K | 68.34M | 30.17K | +5.79% |
| Dec 31, 2023 | GEODE CAPITAL MANAGEMENT, LLC | 1.82% | 511.25K | 63.43M | 28.01K | +5.80% |
| Dec 31, 2023 | WOODLINE PARTNERS LP | 1.72% | 481.98K | 59.79M | 160.04K | +49.71% |
| Dec 31, 2023 | CREDIT SUISSE AG/ | 1.69% | 474.48K | 58.86M | 240.86K | +103.10% |
