| Mar 31, 2024 | IMPAX ASSET MANAGEMENT GROUP PLC | 0.2% | 1.6M | 16.86M | 1.6M | +100.00% |
| Mar 31, 2024 | VANGUARD GROUP INC | 1.01% | 8.11M | 85.44M | 1.03M | +14.57% |
| Mar 31, 2024 | TWO SEAS CAPITAL LP | 0.99% | 7.93M | 83.59M | -577.87K | -6.79% |
| Mar 31, 2024 | BAKER BROS. ADVISORS LP | 0.93% | 7.41M | 78.14M | -179.19K | -2.36% |
| Mar 31, 2024 | SB INVESTMENT ADVISERS (UK) LTD | 9.12% | 73.03M | 769.75M | 0 | 0 |
| Mar 31, 2024 | ABRDN PLC | 0.14% | 1.13M | 11.88M | 0 | 0 |
| Mar 31, 2024 | ASSENAGON ASSET MANAGEMENT S.A. | 0.13% | 1.02M | 10.74M | -44.49K | -4.18% |
| Mar 31, 2024 | RENAISSANCE TECHNOLOGIES LLC | 0.13% | 1.01M | 10.63M | 1.01M | +100.00% |
| Mar 31, 2024 | RHUMBLINE ADVISERS | 0.12% | 957.35K | 10.09M | 535.71K | +127.05% |
| Mar 31, 2024 | JPMORGAN CHASE & CO | 0.12% | 923.8K | 9.74M | 501.36K | +118.68% |
| Mar 31, 2024 | RAFFERTY ASSET MANAGEMENT, LLC | 0.11% | 912.19K | 9.61M | -60.94K | -6.26% |
| Mar 31, 2024 | CITIGROUP INC | 0.11% | 849.05K | 8.95M | 481.14K | +130.78% |
| Mar 31, 2024 | SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) | 0.1% | 762.54K | 8.05M | -174.44K | -18.62% |
| Mar 31, 2024 | PLATINUM INVESTMENT MANAGEMENT LTD | 0.08% | 669.05K | 7.05M | 0 | 0 |
| Mar 31, 2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.05% | 405.4K | 4.27M | 405.4K | +100.00% |
| Mar 31, 2024 | PRIVIUM FUND MANAGEMENT B.V. | 0.07% | 567.8K | 5.98M | 290K | +104.39% |
| Mar 31, 2024 | SWISS NATIONAL BANK | 0.07% | 555.55K | 5.86M | 8.8K | +1.61% |
| Mar 31, 2024 | UBS GROUP AG | 0.07% | 537.6K | 5.67M | 303.71K | +129.85% |
| Mar 31, 2024 | ATIKA CAPITAL MANAGEMENT LLC | 0.07% | 534.98K | 5.64M | -205K | -27.70% |
| Mar 31, 2024 | INVESCO LTD. | 0.06% | 503.57K | 5.31M | -424.48K | -45.74% |
| Mar 31, 2024 | AFFINITY ASSET ADVISORS, LLC | 0.06% | 500K | 5.27M | 0 | 0 |
| Mar 31, 2024 | ALLIANCEBERNSTEIN L.P. | 0.06% | 468.28K | 4.94M | 372.19K | +387.34% |
| Mar 31, 2024 | ALTITUDE CREST PARTNERS INC. | 0.06% | 454.77K | 4.79M | -353.3K | -43.72% |
| Mar 31, 2024 | AMERICAN INTERNATIONAL GROUP, INC. | 0.06% | 450.07K | 4.74M | 444.21K | +7,589.48% |
| Mar 31, 2024 | LEGAL & GENERAL GROUP PLC | 0.05% | 434.34K | 4.58B | 140.38K | +47.75% |
| Mar 31, 2024 | RETIREMENT SYSTEMS OF ALABAMA | 0.05% | 423.49K | 4.46M | 423.49K | +100.00% |
| Mar 31, 2024 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0.05% | 399.88K | 4.21M | 110.07K | +37.98% |
| Mar 31, 2024 | CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. | 0.05% | 372.56K | 3.93M | -526.41K | -58.56% |
| Mar 31, 2024 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 0.49% | 3.93M | 41.47M | -1.34M | -25.41% |
| Mar 31, 2024 | PICTET ASSET MANAGEMENT HOLDING SA | 0.46% | 3.71M | 39.63M | 991.87K | +36.52% |
| Mar 31, 2024 | LOOMIS SAYLES & CO L P | 0.4% | 3.19M | 33.66M | 639.71K | +25.05% |
| Mar 31, 2024 | CITADEL ADVISORS LLC | 0.39% | 3.14M | 33.09M | -342.12K | -9.83% |
| Mar 31, 2024 | ADAR1 CAPITAL MANAGEMENT, LLC | 0.35% | 2.79M | 29.43M | 1.54M | +122.18% |
| Mar 31, 2024 | BVF INC/IL | 0.34% | 2.74M | 28.9M | 0 | 0 |
| Mar 31, 2024 | BANK OF NEW YORK MELLON CORP | 0.33% | 2.63M | 27.7M | 1.31M | +99.32% |
| Mar 31, 2024 | TEJARA CAPITAL LTD | 0.32% | 2.6M | 27.41M | 465.4K | +21.80% |
| Mar 31, 2024 | WHITEFORT CAPITAL MANAGEMENT, LP | 0.3% | 2.39M | 25.2M | 800K | +50.28% |
| Mar 31, 2024 | NUVEEN ASSET MANAGEMENT, LLC | 0.29% | 2.36M | 24.83M | -18.4K | -0.78% |
| Mar 31, 2024 | BANK OF AMERICA CORP /DE/ | 0.28% | 2.25M | 23.72M | 1.49M | +195.54% |
| Mar 31, 2024 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.26% | 2.11M | 22.26M | 89.38K | +4.42% |
| Mar 31, 2024 | BLACKBARN CAPITAL PARTNERS LP | 0.24% | 1.9M | 20.03M | 350.59K | +22.62% |
| Mar 31, 2024 | PROSIGHT MANAGEMENT, LP | 0.23% | 1.86M | 19.6M | 1.86M | +100.00% |
| Mar 31, 2024 | PERTENTO PARTNERS LLP | 0.23% | 1.83M | 19.27M | 948.85K | +107.92% |
| Mar 31, 2024 | LAKEWOOD CAPITAL MANAGEMENT, LP | 0.22% | 1.74M | 18.39M | 660.8K | +60.96% |
| Mar 31, 2024 | FIRST TRUST ADVISORS LP | 0.21% | 1.72M | 18.09M | -1.02M | -37.34% |
| Mar 31, 2024 | NORTHERN TRUST CORP | 0.21% | 1.67M | 17.55M | 185.79K | +12.56% |
| Mar 31, 2024 | PENN DAVIS MCFARLAND INC | 0.2% | 1.64M | 17.29M | 1.64M | +100.00% |
| Mar 31, 2024 | WOODLINE PARTNERS LP | 1.4% | 11.17M | 117.76M | 5.02M | +81.61% |
| Mar 31, 2024 | GHOST TREE CAPITAL, LLC | 0.16% | 1.3M | 13.7M | 700K | +116.67% |
| Mar 31, 2024 | VIKING GLOBAL INVESTORS LP | 8.66% | 69.37M | 731.15M | 0 | 0 |
| Mar 31, 2024 | QVT FINANCIAL LP | 8.33% | 66.72M | 703.23M | -45.82M | -40.72% |
| Mar 31, 2024 | BLACKROCK INC. | 4.52% | 36.19M | 381.42M | 15.38M | +73.93% |
| Mar 31, 2024 | MORGAN STANLEY | 4.45% | 35.64M | 375.6M | 13.71M | +62.52% |
| Mar 31, 2024 | FMR LLC | 4.41% | 35.34M | 372.49M | -1.64M | -4.42% |
| Mar 31, 2024 | RUBRIC CAPITAL MANAGEMENT LP | 2.5% | 20M | 210.8M | 1M | +5.26% |
| Mar 31, 2024 | STATE STREET CORP | 2.14% | 17.15M | 180.79M | 3.43M | +24.96% |
| Mar 31, 2024 | PATIENT SQUARE CAPITAL LP | 1.53% | 12.23M | 128.89M | -411.46K | -3.26% |
| Mar 31, 2024 | GEODE CAPITAL MANAGEMENT, LLC | 0.76% | 6.05M | 63.75M | 522.27K | +9.45% |
| Mar 31, 2024 | ANCHORAGE CAPITAL GROUP, L.L.C. | 0.6% | 4.83M | 50.94M | 0 | 0 |
| Mar 31, 2024 | AVORO CAPITAL ADVISORS LLC | 0.58% | 4.65M | 49.02M | 0 | 0 |
| Mar 31, 2024 | DME CAPITAL MANAGEMENT, LP | 0.52% | 4.19M | 44.17M | 4.19M | +100.00% |
| Mar 31, 2024 | POINTSTATE CAPITAL LP | 0.51% | 4.05M | 42.65M | 4.05M | +100.00% |
| Mar 31, 2024 | STEMPOINT CAPITAL LP | 0.44% | 3.55M | 37.46M | 1.38M | +63.84% |
| Mar 31, 2024 | POLAR CAPITAL HOLDINGS PLC | 0.19% | 1.5M | 15.81M | 1.5M | +100.00% |
| Mar 31, 2024 | GOLDMAN SACHS GROUP INC | 0.19% | 1.5M | 15.8M | 1.09M | +262.85% |
| Mar 31, 2024 | TYRO CAPITAL MANAGEMENT LLC | 0.19% | 1.5M | 15.76M | 149.61K | +11.12% |
| Mar 31, 2024 | RTW INVESTMENTS, LP | 0.18% | 1.45M | 15.33M | 0 | 0 |
| Mar 31, 2024 | PRINCIPAL FINANCIAL GROUP INC | 0.16% | 1.27M | 13.44M | 1.24M | +3,413.90% |
| Mar 31, 2024 | PHILOSOPHY CAPITAL MANAGEMENT LLC | 0.15% | 1.23M | 12.96M | 421.36K | +52.11% |
| Mar 31, 2024 | CLEARBRIDGE INVESTMENTS, LLC | 0.15% | 1.23M | 12.96M | 1.23M | +100.00% |
| Mar 31, 2024 | TIFF ADVISORY SERVICES INC | 0.14% | 1.15M | 12.1M | 1.15M | +100.00% |
| Mar 31, 2024 | UBS ASSET MANAGEMENT AMERICAS INC | 0.14% | 1.14M | 12.06M | -2.2K | -0.19% |
| Mar 31, 2024 | FRANKLIN RESOURCES INC | 0.14% | 1.14M | 12.01M | 1.14M | +100.00% |
| Dec 31, 2023 | NORTHERN TRUST CORP | 0.18% | 1.48M | 16.62M | 30.3K | +2.09% |
| Dec 31, 2023 | RTW INVESTMENTS, LP | 0.17% | 1.45M | 16.33M | -98.44K | -6.34% |
| Dec 31, 2023 | FARALLON CAPITAL MANAGEMENT LLC | 0.87% | 7.34M | 82.38M | 3.48M | +90.38% |
| Dec 31, 2023 | VANGUARD GROUP INC | 0.84% | 7.08M | 79.46M | 1.47M | +26.29% |
| Dec 31, 2023 | WOODLINE PARTNERS LP | 0.73% | 6.15M | 69.08M | -1.02M | -14.25% |
| Dec 31, 2023 | GEODE CAPITAL MANAGEMENT, LLC | 0.65% | 5.52M | 62.05M | 306.4K | +5.87% |
| Dec 31, 2023 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 0.62% | 5.28M | 59.24M | -925K | -14.92% |
| Dec 31, 2023 | ANCHORAGE CAPITAL GROUP, L.L.C. | 0.57% | 4.83M | 54.27M | 0 | 0 |
| Dec 31, 2023 | AVORO CAPITAL ADVISORS LLC | 0.55% | 4.65M | 52.23M | 0 | 0 |
| Dec 31, 2023 | PRICE T ROWE ASSOCIATES INC /MD/ | 0.45% | 3.79M | 42.52M | 74.13K | +2.00% |
| Dec 31, 2023 | NORGES BANK | 0.44% | 3.7M | 41.51M | 3.7M | +100.00% |
| Dec 31, 2023 | CITADEL ADVISORS LLC | 0.41% | 3.48M | 39.1M | 3.36M | +2,658.81% |
| Dec 31, 2023 | BVF INC/IL | 0.32% | 2.74M | 30.8M | 0 | 0 |
| Dec 31, 2023 | FIRST TRUST ADVISORS LP | 0.32% | 2.74M | 30.76M | 2.23M | +434.79% |
| Dec 31, 2023 | LOOMIS SAYLES & CO L P | 0.3% | 2.55M | 28.68M | 568.7K | +28.65% |
| Dec 31, 2023 | OCTAGON CAPITAL ADVISORS LP | 0.3% | 2.49M | 28.01M | -1.87M | -42.89% |
| Dec 31, 2023 | SLATE PATH CAPITAL LP | 0.29% | 2.46M | 27.63M | 2.46M | +100.00% |
| Dec 31, 2023 | NUVEEN ASSET MANAGEMENT, LLC | 0.28% | 2.37M | 26.66M | 940.32K | +65.59% |
| Dec 31, 2023 | | 0.15% | 1.26M | 14.11M | 1.26M | +100.00% |
| Dec 31, 2023 | TEJARA CAPITAL LTD | 0.25% | 2.13M | 23.97M | 1.78M | +495.39% |
| Dec 31, 2023 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.24% | 2.02M | 22.72M | 99.15K | +5.15% |
| Dec 31, 2023 | LAURION CAPITAL MANAGEMENT LP | 0.22% | 1.89M | 21.18M | 850.45K | +82.13% |
| Dec 31, 2023 | WHITEFORT CAPITAL MANAGEMENT, LP | 0.19% | 1.59M | 17.87M | 1.59M | +100.00% |
| Dec 31, 2023 | SC CHINA HOLDING LTD | 0.16% | 1.35M | 14.06M | 0 | 0 |
| Dec 31, 2023 | BANK OF NEW YORK MELLON CORP | 0.16% | 1.32M | 14.81M | 130.59K | +10.99% |
| Dec 31, 2023 | PFM HEALTH SCIENCES, LP | 0.14% | 1.22M | 13.64M | 0 | 0 |
| Dec 31, 2023 | UBS ASSET MANAGEMENT AMERICAS INC | 0.14% | 1.15M | 12.88M | 97.43K | +9.29% |
| Dec 31, 2023 | EVENTIDE ASSET MANAGEMENT, LLC | 0.14% | 1.14M | 12.85M | -546.36K | -32.32% |
| Dec 31, 2023 | ABRDN PLC | 0.13% | 1.13M | 12.66M | 1.13M | +100.00% |
| Dec 31, 2023 | FOUNDERS FUND VI MANAGEMENT, LLC | 0.13% | 1.12M | 12.57M | 0 | 0 |
| Dec 31, 2023 | MILLENNIUM MANAGEMENT LLC | 0.13% | 1.11M | 12.46M | -1.13M | -50.39% |
| Dec 31, 2023 | LAKEWOOD CAPITAL MANAGEMENT, LP | 0.13% | 1.08M | 12.17M | 1.08M | +100.00% |
| Dec 31, 2023 | BAKER BROS. ADVISORS LP | 0.9% | 7.59M | 85.27M | -4.28M | -36.07% |
| Dec 31, 2023 | QVT FINANCIAL LP | 13.33% | 112.54M | 1.26B | 0 | 0 |
| Dec 31, 2023 | SB INVESTMENT ADVISERS (UK) LTD | 8.65% | 73.03M | 820.15M | 0 | 0 |
| Dec 31, 2023 | VIKING GLOBAL INVESTORS LP | 8.21% | 69.37M | 779.01M | -4.07M | -5.54% |
| Dec 31, 2023 | FMR LLC | 4.38% | 36.98M | 415.24M | -1.93M | -4.97% |
| Dec 31, 2023 | MORGAN STANLEY | 2.6% | 21.93M | 246.24M | 2.62M | +13.54% |
| Dec 31, 2023 | BLACKROCK INC. | 2.46% | 20.81M | 233.65M | 3.08M | +17.39% |
| Dec 31, 2023 | RUBRIC CAPITAL MANAGEMENT LP | 2.25% | 19M | 213.37M | 8.5M | +80.95% |
| Dec 31, 2023 | STATE STREET CORP | 1.63% | 13.73M | 154.16M | 3.41M | +33.01% |
| Dec 31, 2023 | WELLINGTON MANAGEMENT GROUP LLP | 1.62% | 13.64M | 153.18M | 13.64M | +100.00% |
| Dec 31, 2023 | PATIENT SQUARE CAPITAL LP | 1.5% | 12.64M | 141.95M | 0 | 0 |
| Dec 31, 2023 | TWO SEAS CAPITAL LP | 1.01% | 8.51M | 95.55M | 592.99K | +7.49% |
