| 2024-03-31 | BNP PARIBAS ARBITRAGE, SNC | 0.02% | 20.58K | 70.99K | -111.63K | -84.44% |
| 2024-03-31 | STRS OHIO | 0.01% | 8.2K | 28K | -500 | -5.75% |
| 2024-03-31 | LEGAL & GENERAL GROUP PLC | 0% | 3.97K | 13.71M | 0 | 0 |
| 2024-03-31 | FMR LLC | 0% | 3.54K | 12.2K | 24 | +0.68% |
| 2024-03-31 | AMERITAS INVESTMENT PARTNERS, INC. | 0% | 3.44K | 11.86M | 0 | 0 |
| 2024-03-31 | METROPOLITAN LIFE INSURANCE CO/NY | 0% | 2.34K | 8.06K | 2.34K | +100.00% |
| 2024-03-31 | NBC SECURITIES, INC. | 0% | 2K | 6K | 0 | 0 |
| 2024-03-31 | AMALGAMATED BANK | 0% | 1.4K | 5K | -2.23K | -61.36% |
| 2024-03-31 | FEDERATED HERMES, INC. | 0% | 773 | 2.67K | -177 | -18.63% |
| 2024-03-31 | FARTHER FINANCE ADVISORS, LLC | 0% | 55 | 185 | 55 | +100.00% |
| 2024-03-31 | NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC | 0% | 6 | 20 | 6 | +100.00% |
| 2024-03-31 | OPALEYE MANAGEMENT INC. | 2.67% | 2.65M | 9.13M | 110K | +4.34% |
| 2024-03-31 | BLACKROCK INC. | 2.4% | 2.38M | 8.2M | 55.99K | +2.41% |
| 2024-03-31 | VANGUARD GROUP INC | 2.33% | 2.3M | 7.95M | 60.25K | +2.69% |
| 2024-03-31 | LOGOS GLOBAL MANAGEMENT LP | 2.22% | 2.2M | 7.59M | 2.2M | +100.00% |
| 2024-03-31 | BIOIMPACT CAPITAL LLC | 1.35% | 1.34M | 4.63M | 1.34M | +100.00% |
| 2024-03-31 | GEODE CAPITAL MANAGEMENT, LLC | 0.91% | 897.97K | 3.1M | 48.08K | +5.66% |
| 2024-03-31 | SILVERARC CAPITAL MANAGEMENT, LLC | 0.85% | 844.24K | 2.91M | -19.65K | -2.27% |
| 2024-03-31 | STATE STREET CORP | 0.81% | 798.25K | 2.75M | 57.06K | +7.70% |
| 2024-03-31 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0.75% | 740.13K | 2.55M | -169.97K | -18.68% |
| 2024-03-31 | CHECKPOINT CAPITAL L.P. | 0.51% | 506.08K | 1.75M | -786.23K | -60.84% |
| 2024-03-31 | NORTHERN TRUST CORP | 0.33% | 327.69K | 1.13M | 13.51K | +4.30% |
| 2024-03-31 | PROPEL BIO MANAGEMENT, LLC | 0.26% | 260K | 897K | 260K | +100.00% |
| 2024-03-31 | SIMPLIFY ASSET MANAGEMENT INC. | 0.2% | 200K | 690K | 200K | +100.00% |
| 2024-03-31 | J. GOLDMAN & CO LP | 0.14% | 137.87K | 475.66K | 0 | 0 |
| 2024-03-31 | BANK OF NEW YORK MELLON CORP | 0.13% | 128.63K | 443.76K | -4.75K | -3.56% |
| 2024-03-31 | RENAISSANCE TECHNOLOGIES LLC | 0.12% | 116.84K | 403K | -425.86K | -78.47% |
| 2024-03-31 | SHAY CAPITAL LLC | 0.11% | 113.66K | 392.13K | 113.66K | +100.00% |
| 2024-03-31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.11% | 107.71K | 371.59K | 0 | 0 |
| 2024-03-31 | PFS PARTNERS, LLC | 0.1% | 99K | 341.55K | 0 | 0 |
| 2024-03-31 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.1% | 96.48K | 332.86K | -115K | -54.38% |
| 2024-03-31 | NUVEEN ASSET MANAGEMENT, LLC | 0.08% | 74.85K | 258.23K | 0 | 0 |
| 2024-03-31 | MORGAN STANLEY | 0.07% | 68.23K | 235.38K | -80.78K | -54.21% |
| 2024-03-31 | WEALTHTRUST AXIOM LLC | 0.06% | 63.5K | 219.08K | 0 | 0 |
| 2024-03-31 | OPPENHEIMER & CO INC | 0.06% | 60.42K | 208.43K | 60.42K | +100.00% |
| 2024-03-31 | RHUMBLINE ADVISERS | 0.05% | 51.96K | 179.24K | 491 | +0.95% |
| 2024-03-31 | ATOM INVESTORS LP | 0.05% | 45.74K | 157.79K | 6.09K | +15.36% |
| 2024-03-31 | BAILARD, INC. | 0.04% | 40.9K | 141.11K | 40.9K | +100.00% |
| 2024-03-31 | GOLDMAN SACHS GROUP INC | 0.04% | 37.97K | 131.01K | 14.06K | +58.79% |
| 2024-03-31 | TEJARA CAPITAL LTD | 0.04% | 37.48K | 129.31K | -1.23M | -97.05% |
| 2024-03-31 | TRUST CO OF TOLEDO NA /OH/ | 0.04% | 36.5K | 125.93K | 0 | 0 |
| 2024-03-31 | LPL FINANCIAL LLC | 0.04% | 36K | 124.2K | 36K | +100.00% |
| 2024-03-31 | CITADEL ADVISORS LLC | 0.03% | 28.68K | 98.95K | -156.38K | -84.50% |
| 2024-03-31 | UNITED BANK | 0.03% | 28.45K | 98.15K | 0 | 0 |
| 2024-03-31 | JPMORGAN CHASE & CO | 0.03% | 25.46K | 87.85K | -1.52K | -5.63% |
| 2024-03-31 | DIMENSIONAL FUND ADVISORS LP | 0.02% | 22.74K | 78.44K | 22.74K | +100.00% |
| 2024-03-31 | METLIFE INVESTMENT MANAGEMENT, LLC | 0.02% | 22.69K | 78.29K | 22.69K | +100.00% |
| 2024-03-31 | BANK OF AMERICA CORP /DE/ | 0.02% | 21.98K | 75.82K | -20.02K | -47.67% |
| 2024-03-31 | AMERIPRISE FINANCIAL INC | 0.02% | 21.61K | 74.55K | 21.61K | +100.00% |
| 2024-03-31 | AMERICAN INTERNATIONAL GROUP, INC. | 0.02% | 20.77K | 71.67K | -178 | -0.85% |
| 2024-03-31 | NEA MANAGEMENT COMPANY, LLC | 11.48% | 11.37M | 39.23M | 0 | 0 |
| 2024-03-31 | FRAZIER LIFE SCIENCES MANAGEMENT, L.P. | 7.45% | 7.38M | 25.46M | 0 | 0 |
| 2024-03-31 | RUBRIC CAPITAL MANAGEMENT LP | 5.62% | 5.56M | 19.2M | -120.3K | -2.12% |
| 2024-03-31 | VIKING GLOBAL INVESTORS LP | 4.44% | 4.4M | 15.18M | 0 | 0 |
| 2024-03-31 | VR ADVISER, LLC | 3.46% | 3.42M | 11.81M | 278 | +0.01% |
| 2024-03-31 | MAI CAPITAL MANAGEMENT | 1.14% | 1.13M | 3.9M | -147.64K | -11.54% |
| 2024-03-31 | ROSALIND ADVISORS, INC. | 0.94% | 926.02K | 3.19M | -936.41K | -50.28% |
| 2024-03-31 | AMERICAN CENTURY COMPANIES INC | 0.05% | 46.21K | 159.41K | 25.14K | +119.37% |
| 2024-03-31 | UBS GROUP AG | 0.04% | 42.12K | 145.31K | 10.74K | +34.23% |
| 2024-03-31 | BARCLAYS PLC | 0.04% | 35.2K | 122K | -28.6K | -44.83% |
| 2024-03-31 | INVESCO LTD. | 0.02% | 19.89K | 68.61K | 0 | 0 |
| 2024-03-31 | JUMP FINANCIAL, LLC | 0.02% | 18.44K | 63.62K | 18.44K | +100.00% |
| 2024-03-31 | WELLS FARGO & COMPANY/MN | 0.02% | 16.84K | 58.1K | 3.88K | +29.91% |
| 2024-03-31 | NEW YORK STATE COMMON RETIREMENT FUND | 0.02% | 15.06K | 52K | -21.64K | -58.97% |
| 2024-03-31 | SG AMERICAS SECURITIES, LLC | 0.01% | 14.59K | 50K | -83.66K | -85.15% |
| 2024-03-31 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0.01% | 13.07K | 45.11K | 13.07K | +100.00% |
| 2024-03-31 | STIFEL FINANCIAL CORP | 0.01% | 10.1K | 34.86K | 3 | +0.03% |
| 2024-03-31 | RAYMOND JAMES & ASSOCIATES | 0.01% | 10K | 34.5K | 10K | +100.00% |
| 2024-03-31 | CITIGROUP INC | 0.01% | 8.7K | 30.03K | 1.75K | +25.12% |
| 2023-12-31 | FRAZIER LIFE SCIENCES MANAGEMENT, L.P. | 7.43% | 7.38M | 9.89M | 500K | +7.27% |
| 2023-12-31 | RUBRIC CAPITAL MANAGEMENT LP | 5.72% | 5.68M | 7.62M | 0 | 0 |
| 2023-12-31 | VIKING GLOBAL INVESTORS LP | 4.43% | 4.4M | 5.9M | 0 | 0 |
| 2023-12-31 | VR ADVISER, LLC | 3.45% | 3.42M | 4.59M | 0 | 0 |
| 2023-12-31 | OPALEYE MANAGEMENT INC. | 2.55% | 2.54M | 3.4M | 829.1K | +48.60% |
| 2023-12-31 | BLACKROCK INC. | 2.34% | 2.32M | 3.11M | 171.45K | +7.98% |
| 2023-12-31 | VANGUARD GROUP INC | 2.26% | 2.24M | 3.01M | 285.52K | +14.58% |
| 2023-12-31 | ROSALIND ADVISORS, INC. | 1.88% | 1.86M | 2.5M | 1.86M | +100.00% |
| 2023-12-31 | | 0.1% | 99K | 132.66K | -1K | -1.00% |
| 2023-12-31 | MAI CAPITAL MANAGEMENT | 1.29% | 1.28M | 1.71M | -171.94K | -11.85% |
| 2023-12-31 | TEJARA CAPITAL LTD | 1.28% | 1.27M | 1.7M | 1.09M | +604.11% |
| 2023-12-31 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0.92% | 910.09K | 1.22M | 910.09K | +100.00% |
| 2023-12-31 | SILVERARC CAPITAL MANAGEMENT, LLC | 0.87% | 863.88K | 1.16M | -63.53K | -6.85% |
| 2023-12-31 | GEODE CAPITAL MANAGEMENT, LLC | 0.86% | 849.88K | 1.14M | 62.24K | +7.90% |
| 2023-12-31 | STATE STREET CORP | 0.75% | 741.19K | 993.2K | 32.6K | +4.60% |
| 2023-12-31 | RENAISSANCE TECHNOLOGIES LLC | 0.55% | 542.7K | 727K | 475.4K | +706.39% |
| 2023-12-31 | ANSON FUNDS MANAGEMENT LP | 0.42% | 420.8K | 563.88K | 420.8K | +100.00% |
| 2023-12-31 | NORTHERN TRUST CORP | 0.32% | 314.18K | 421K | -1.38K | -0.44% |
| 2023-12-31 | TANG CAPITAL MANAGEMENT LLC | 0.3% | 300K | 402K | 300K | +100.00% |
| 2023-12-31 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.21% | 211.48K | 283.39K | 25K | +13.41% |
| 2023-12-31 | CITADEL ADVISORS LLC | 0.19% | 185.06K | 247.98K | 157.98K | +583.35% |
| 2023-12-31 | MORGAN STANLEY | 0.15% | 149K | 199.66K | 114.29K | +329.23% |
| 2023-12-31 | J. GOLDMAN & CO LP | 0.14% | 137.87K | 184.75K | 0 | 0 |
| 2023-12-31 | BANK OF NEW YORK MELLON CORP | 0.13% | 133.38K | 178.73K | -699 | -0.52% |
| 2023-12-31 | BNP PARIBAS ARBITRAGE, SNC | 0.13% | 132.21K | 177.16K | 122.54K | +1,267.77% |
| 2023-12-31 | MILLENNIUM MANAGEMENT LLC | 0.12% | 119.79K | 160.52K | 119.79K | +100.00% |
| 2023-12-31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.11% | 107.71K | 144.33K | 0 | 0 |
| 2023-12-31 | SQUAREPOINT OPS LLC | 0.1% | 99.49K | 133.32K | 99.49K | +100.00% |
| 2023-12-31 | SG AMERICAS SECURITIES, LLC | 0.1% | 98.25K | 132K | 78.66K | +401.37% |
| 2023-12-31 | NUVEEN ASSET MANAGEMENT, LLC | 0.08% | 74.85K | 100.3K | 7.91K | +11.82% |
| 2023-12-31 | JANE STREET GROUP, LLC | 0.07% | 65.95K | 88.38K | 41.35K | +168.10% |
| 2023-12-31 | BARCLAYS PLC | 0.06% | 63.8K | 86K | 50.51K | +380.22% |
| 2023-12-31 | WEALTHTRUST AXIOM LLC | 0.06% | 63.5K | 85.09K | -30K | -32.09% |
| 2023-12-31 | RHUMBLINE ADVISERS | 0.05% | 51.46K | 68.95K | -2.81K | -5.17% |
| 2023-12-31 | BANK OF AMERICA CORP /DE/ | 0.04% | 41.99K | 56.27K | 13.3K | +46.35% |
| 2023-12-31 | ATOM INVESTORS LP | 0.04% | 39.65K | 53.13K | 1.13K | +2.93% |
| 2023-12-31 | NEW YORK STATE COMMON RETIREMENT FUND | 0.04% | 36.7K | 49K | -83 | -0.23% |
| 2023-12-31 | TRUST CO OF TOLEDO NA /OH/ | 0.04% | 36.5K | 48.91K | -80.64K | -68.84% |
| 2023-12-31 | UBS GROUP AG | 0.03% | 31.38K | 42.05K | 8.8K | +38.99% |
| 2023-12-31 | UNITED BANK | 0.03% | 28.45K | 38.12K | 0 | 0 |
| 2023-12-31 | JPMORGAN CHASE & CO | 0.03% | 26.98K | 36.16K | -2 | -0.01% |
| 2023-12-31 | GOLDMAN SACHS GROUP INC | 0.02% | 23.92K | 32.05K | -2.24K | -8.55% |
| 2023-12-31 | AMERICAN CENTURY COMPANIES INC | 0.02% | 21.06K | 28.22K | -364 | -1.70% |
| 2023-12-31 | AMERICAN INTERNATIONAL GROUP, INC. | 0.02% | 20.95K | 28.07K | 176 | +0.85% |
| 2023-12-31 | INVESCO LTD. | 0.02% | 19.89K | 26.65K | 3.84K | +23.94% |
| 2023-12-31 | ROYAL BANK OF CANADA | 0.01% | 14.2K | 19K | 7.21K | +103.15% |
| 2023-12-31 | WELLS FARGO & COMPANY/MN | 0.01% | 12.96K | 17.37K | 2.69K | +26.15% |
| 2023-12-31 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 0.01% | 10.95K | 14.67K | 10.95K | +100.00% |
| 2023-12-31 | NEA MANAGEMENT COMPANY, LLC | 11.45% | 11.37M | 15.24M | 0 | 0 |
